Phospho-Jak1 (Tyr1034/1035) Rabbit APC Conjugate

• Description:

  Phospho-Jak1 (Tyr1034/1035) Rabbit APC Conjugate _x000D_ Catalog number: B2018839_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 10 ug_x000D_ Molecular Weight or Concentration: N/A_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: 2-8°C_x000D_ Keywords: Tyrosine-protein kinase JAK1, Janus kinase 1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Tavoletti G, Avallone G, Conforti C, Roccuzzo G, Maronese CA, Mattioli MA, Quaglino P, Zalaudek I, Marzano AV, Ribero S, Alberti-Violetti S. Topical ruxolitinib: A new treatment for vitiligo J Eur Acad Dermatol Venereol. 2023 Nov;37(11):2222-2230._x000D_ 2: Kikkawa K, Matsuda T, Fujimuro M, Sekine Y. The Atypical Dual Specificity Phosphatase DUSP15 Regulates Jak1-Mediated STAT3 Activation Biol Pharm Bull. 2024;47(9):1487-1493._x000D_ 3: Pardanani A, Gotlib J, Roberts AW, Wadleigh M, Sirhan S, Kawashima J, Maltzman JA, Shao L, Gupta V, Tefferi A. Long-term efficacy and safety of momelotinib, a JAK1 and JAK2 inhibitor, for the treatment of myelofibrosis Leukemia. 2018 Apr;32(4):1035-1038._x000D_ 4: Ostojic A, Vrhovac R, Verstovsek S. Ruxolitinib: a new JAK1/2 inhibitor that offers promising options for treatment of myelofibrosis Future Oncol. 2011 Sep;7(9):1035-43._x000D_ 5: Sk MF, Jonniya NA, Roy R, Kar P. Phosphorylation-Induced Conformational Dynamics and Inhibition of Janus Kinase 1 by Suppressors of Cytokine Signaling 1 J Phys Chem B. 2022 May 5;126(17):3224-3239._x000D_ 6: Runtsch MC, Angiari S, Hooftman A, Wadhwa R, Zhang Y, Zheng Y, Spina JS, Ruzek MC, Argiriadi MA, McGettrick AF, Mendez RS, Zotta A, Peace CG, Walsh A, Chirillo R, Hams E, Fallon PG, Jayamaran R, Dua K, Brown AC, Kim RY, Horvat JC, Hansbro PM, Wang C, O'Neill LAJ. Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages Cell Metab. 2022 Mar 1;34(3):487-501.e8._x000D_ 7: Pan Y, Shu G, Fu L, Huang K, Zhou X, Gui C, Liu H, Jin X, Chen M, Li P, Cen J, Feng Z, Lu J, Chen Z, Li J, Xu Q, Wang Y, Liang H, Wang Z, Deng Q, Chen W, Luo J, Yang J, Zhang J, Wei J. EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing JAK1 Adv Sci (Weinh). 2023 Apr;10(11):e2206792._x000D_ 8: Heuschkel MJ, Bach C, Meiss-Heydmann L, Gerges E, Felli E, Giannone F, Pessaux P, Schuster C, Lucifora J, Baumert TF, Verrier ER. JAK1 promotes HDV replication and is a potential target for antiviral therapy J Hepatol. 2024 Feb;80(2):220-231._x000D_ 9: Abreu MT. JAK1 Inhibition to Treat Crohn's Disease N Engl J Med. 2023 May 25;388(21):2005-2009._x000D_ 10: Hernandez LM, Montersino A, Niu J, Guo S, Faezov B, Sanders SS, Dunbrack RL, Thomas GM. Palmitoylation-dependent control of JAK1 kinase signaling governs responses to neuropoietic cytokines and survival in DRG neurons J Biol Chem. 2023 Aug;299(8):104965. _x000D_ _x000D_ Products Related to Phospho-Jak1 (Tyr1034/1035) Rabbit APC Conjugate can be found at Conjugates

• Short Description:

  Catalog Number: B2018839 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5