CD26 (202-36), CF740 conjugate, 0.1mg/mL

CAT: 0037-BNC740888-500Size: 1x 500 µLDry Ice: NoHazardous: No
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Description
Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI; Code: N-L039) . It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
ADA-binding protein (ADABP) ; Adenosine deaminase complexing protein 2 (ADCP-2) ; Dipeptidyl peptidase 4; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; Dipeptidyl peptidase, intestinal; Dipeptidylpeptidase 4; Dipeptidylpeptidase IV; DPP4; DPPIV; Intestinal dipeptidyl peptidase; T-cell activation antigen CD26; TP103
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
DPP4
Gene ID
1803
NCBI Gene ID
368912
UniProt
P27487
Swiss Prot
P27487
Host
Mouse
Species Reactivity
Human, Rat
Reactivity
CD26
Immunogen
Human T cell clone
Target Antigen
CD26
Clonality
Monoclonal
Clone
202-36
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published) |IF (published)
Field of Research
Immunology
Positive Control
YT, HEP-G2 cells, and lymphocytes. Lymph nodes and tonsils.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
~110 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Cancer Res (2005) 65(15): 6950-6. (functional studies) J Biol Chem (2001) 276(22): 19532-19539. (Flow) BMC Cancer (2011) 11:51. (IF)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740
Product Datasheet
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