mGluR2 agonist 1 (hydrochloride)

• UNSPSC Description:

  mGluR2 agonist 1 hydrochloride is a potent selective agonist for metabotropic glutamate receptors mGluR 2 with EC50 of 82 nM[1].

• Target Antigen:

  mGluR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mglur2-agonist-1-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@]1(C(O)=O)[C@H]([C@H](N)C(O)=O)C1.Cl

• Molecular Weight:

  209.63

• References & Citations:

  [1]Staudt M, et al., Synthesis and pharmacological characterization of conformationally restricted 2-amino-Adipic acid analogs and carboxycyclopropyl glycines as selective metabotropic glutamate 2 receptor agonists. Eur J Med Chem. 2024 Feb 15;266:116157.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported