SCD1 Inhibitor

• Description:

  Cell-permeable. A potent and selective inhibitor of SCD1(stearoyl-CoA desaturase 1) (In vitro: IC₅₀ = 37 nM for hSCD1, <4 nM for mSCD1). Also exhibited in vivo efficacy with dose-dependent desaturation index lowering effect. SCD1 inhibition resulted in alterations in macrophage membrane lipid composition and marked hypersensitivity to toll-like receptor 4 agonists.

• Shipping Conditions:

  gel pack

• Storage Conditions:

  -20°C

• Shelf Life:

  24 months