XAF1 Antibody

• Catalog number
  R30321
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  XAF1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the XAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This XAF1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q6GPH4
• Purity
  Antigen affinity
• Description
  XIAP associated factor-1, also known as XAF1, is a human gene. X-linked inhibitor of apoptosis(XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP(BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells. And alteration in XAF1 and XIAP RNA expression levels may lead to increased apoptotic resistance and proliferation due to unregulated XIAP function in cancer cells.
• Immunogen
  An amino acid sequence from the C-terminus of human XAF1 (QEKCRWLASSKGKQVRNFS) was used as the immunogen for this XAF1 antibody.
• Storage
  After reconstitution, the XAF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  XAF1  
• Gene symbol
  XAF1
• Short name
  Anti-XAF1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to XAF1
• Alternative technique
  antibodies
• Alternative to gene target
  XIAP associated factor 1, XAF1 and IDBG-22619 and ENSG00000132530 and 54739, zinc ion binding, nuclei, Xaf1 and IDBG-196515 and ENSMUSG00000040483 and 327959, XAF1 and IDBG-633696 and ENSBTAG00000011343 and 509740

Gene info

• Identity
  HGNC:30932
• Gene
  XAF1
• Long gene name
  XIAP associated factor 1
• Synonyms
  • BIRC4BP
  • XIAPAF1
  • HSXIAPAF1
• GenBank acession
  • X99699
• Locus
  17p13.2
• Discovery year
  2008-03-04
• Entrez gene record
  54739
• Pubmed identfication
  • 12029096
  • 11175744
• RefSeq identity
  • NM_017523
• VEGA ID
  OTTHUMG00000177908

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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