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Target antigen
Wnt4
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human, rat Predicted to work with: mouse
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Analyses
WB
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Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Wnt4(232-249aa HALKEKFDGATEVEPRRV), identical to the related mouse and rat sequences.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the Wnt4 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The Wnt4 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Wingless-type MMIV integration site family, member4, is a secreted protein that in humans is encoded by the Wnt4 gene. By fluorescence in situ hybridization, WNT4 gene was mapped to chromosome 1p35, a location consistent with the results of radiation hybrid mapping. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and embryogenesis.
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Related articles
1. Biason-Lauber, A., De Filippo, G., Konrad, D., Scarano, G., Nazzaro, A., Schoenle, E. J. WNT4 deficiency--a clinical phenotype distinct from the classic Mayer-Rokitansky-Kuster-Hauser syndrome: a case report. Hum. Reprod. 22: 224-229, 2007. 2. Biason-Lauber, A., Konrad, D., Navratil, F., Schoenle, E. J. A WNT4 mutation associated with mullerian-duct regression and virilization in a 46,XX woman. New Eng. J. Med. 351: 792-798, 2004. 3. Garnis, C., Campbell, J., Davies, J. J., MacAulay, C., Lam, S., Lam, W. L. Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis. Hum. Molec. Genet. 14: 475-482, 2005.
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Gene Name
WNT4
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Protein Name
Protein Wnt-4
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Gene Full Name
wingless-type MMTV integration site family, member 4
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Synonyms
MGC123964 antibody|Protein Wnt-4 antibody|RP23-246F18.1 antibody|Wingless type MMTV integration site family member 4 precursor antibody|WNT 4 antibody|WNT 4 protein precursor antibody|WNT4 antibody|WNT4_HUMAN antibody
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Uniprot ID
P56705
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
