RP2 3'UTR Lenti-reporter-Luc Virus

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Technical file

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Notes

Designed for Research Use Only. Manufactured in Canada.
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Description

Lenti kit or vector with CMV or EF promotors for producing Lentivirus (lenti-, Latin for "slow") or lentiviral particles in 293t cells. Lentiviruses are characterized by a long incubation period and often Puro selected. Lentiviruses can deliver a significant amount of viral RNA into the DNA of the host cell and have the unique ability among retroviruses of being able to infect non-dividing cells. They are one of the most efficient methods of a gene delivery vector. The are packaged in HEK 293T cells to get the highest possible lentiviral titers of 108 IFU/ml. The Luc reporter is the expression of the firefly luciferase gene. Puro stands for puromicin selection.

Identity

HGNC:32036
Gene

NUDT19
Long gene name

nudix hydrolase 19
Synonyms gene name
- nudix (nucleoside diphosphate linked moiety X)-type motif 19
Synonyms
- RP2
Locus

19q13.11
Discovery year

2005-07-07
Entrez gene record

390916
RefSeq identity
- NM_001105570
Classification
- Nudix hydrolase family
VEGA ID

OTTHUMG00000180228

Identity

HGNC:17792
Gene

VTI1A
Long gene name

vesicle transport through interaction with t-SNAREs 1A
Synonyms gene name
- vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
Synonyms
- MVti1
- Vti1-rp2
GenBank acession
- BC017052
Locus

10q25.2
Discovery year

2002-11-22
Entrez gene record

143187
Pubmed identfication
- 9446565
Classification
- SNAREs
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000019063

Identity

HGNC:5999
Gene

IL1RL2
Long gene name

interleukin 1 receptor like 2
Synonyms
- IL1R-rp2
- IL1RRP2
GenBank acession
- U49065
Locus

2q12.1
Discovery year

1998-12-17
Entrez gene record

8808
Pubmed identfication
RefSeq identity
- NM_003854
Classification
- Immunoglobulin like domain containing
- Interleukin receptors
- TIR domain containing
VEGA ID

OTTHUMG00000130776

Identity

HGNC:10274
Gene

RP2
Long gene name

RP2 activator of ARL3 GTPase
Synonyms gene name
- retinitis pigmentosa 2 (X-linked recessive)
- RP2, ARL3 GTPase activating protein
Synonyms
- TBCCD2
- NME10
- NM23-H10
GenBank acession
- AJ007590
Locus

Xp11.3
Discovery year

2001-06-22
Entrez gene record

6102
Pubmed identfication
- 18376416
- 6325945
- 9697692
- 19852809
RefSeq identity
- NM_006915
VEGA ID

OTTHUMG00000021430
Locus Specific Databases
- Mutations of the RP2 Gene
- Global Variome shared LOVD

Name

Artificial Gene Fusion
Concept

Scope note: The in vitro fusion of GENES by RECOMBINANT DNA techniques to analyze protein behavior or GENE EXPRESSION REGULATION, or to merge protein functions for specific medical or industrial uses.
Tree numbers
- E05.393.220.250
Qualifiers

drug effects, methods, radiation effects