Supervillin Antibody

• Catalog number
  bs-7123R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Supervillin Primary Polyclonal Antibody
• Also known as
  Supervillin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Supervillin
• Specificity
  This is a highly specific antibody against Supervillin.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  80-130/2214
• Subcellular location
  Cell membrane
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Supervillin
• Gene ID number
  6840
• Swiss Prot
  O95425
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Supervillin; Archvillin; p205/p250; SVIL
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Supervillin  
• Gene symbol
  SVIL2P, SVIL
• Short name
  Anti-Supervillin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Supervillin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:44959
• Gene
  SVIL2P
• Long gene name
  supervillin family member 2, pseudogene
• Synonyms gene
  • SVILP1
• Synonyms gene name
  • supervillin pseudogene 1
• Locus
  10p11.23
• Discovery year
  2012-12-20
• Entrez gene record
  645954
• RefSeq identity
  • NR_036438
• VEGA ID
  OTTHUMG00000017900

Gene info

• Identity
  HGNC:11480
• Gene
  SVIL
• Long gene name
  supervillin
• Synonyms name
  • archvillin
• GenBank acession
  • AF051851
• Locus
  10p11.23
• Discovery year
  1998-05-07
• Entrez gene record
  6840
• Pubmed identfication
  • 9382871
• Classification
  • Gelsolin/villins
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000017882

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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