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Alternative_name
4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester; BPD-MA
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Description
Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. More recently, Verteporfin has been identified as an inhibitor of YAP-TEAD interaction. Also suppresses cancer stem cell properties in vitro.
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CAS Number
129497-78-5
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Structure Available
Yes
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Molecular Formula
C₄₁H₄₂N₄O₈
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Molecular Weight
718.79
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Cell Permeable
Yes
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Purity
≥98% by HPLC
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Solubilities
DMSO (>10 mg/ml)
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Handling
Protect from air and light
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Tag Line
A photosensitizer and cancer stem cell inhibitor
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Storage Condition
-20°C
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Shipping Condition
Gel Pack
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Shelf Life
36 months
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PubChem CID
5362420
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SMILES
CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C
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InChi
InChI=1S/C41H42N4O8/c1-9-23-20(2)29-17-34-27-13-10-26(39(49)52-7)38(40(50)53-8)41(27,5)35(45-34)19-30-22(4)25(12-15-37(48)51-6)33(44-30)18-32-24(11-14-36(46)47)21(3)28(43-32)16-31(23)42-29/h9-10,13,16-19,38,42,44H,1,11-12,14-15H2,2-8H3,(H,46,47)/t38-,41+/m0/s1
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InChi Key
YTZALCGQUPRCGW-ZSFNYQMMSA-N
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MSDS Available
Yes