VEGFR2 Antibody ( KDR1)

• Catalog number
  MA1040
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  VEGFR2
• Clonality
  Monoclonal antibody
• Clone
  KDR-1
• Raised in
  mice
• Type of the antibody
  IgG1 monoclonal antibody
• Product form
  freeze-dried
• Reacts with species
  Human
• Analyses
  IHC-F
• Immunogen
  Recombinant human extracellular domain of VEGFR-2(KDR).
• Product configuration
  Mouse ascites fluid, 1.2% Na acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
• Purification
  Ascites
• Solubilization
  The powdered antibody should be dissolved in 1ml of PBS buffer to achieve final concentration of 100ug/ml.
• Storage condtions
  Keep the VEGFR2 Antibody ( KDR1)at minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The VEGFR2 Antibody ( KDR1) did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. The importance of VEGF and its receptor system in tumor growth and intervention in this system may provide promising approaches to cancer therapy. VEGF receptor 2 is a member of a receptor tyrosine kinase family. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues.
• Related articles
  1. Folkman, J. : Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Med. 1: 27-31, 1995. 2. Millauer, B.; Shawver, L. K.; Plate, K. H.; Risau, W.; Ullrich, A. : Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 367: 576-579, 1994.
• Gene Name
  KDR
• Protein Name
  Vascular endothelial growth factor receptor 2
• Gene Full Name
  kinase insert domain receptor(a type III receptor tyrosine kinase)
• Synonyms
  CD309|VEGFR|FLK1|VEGFR2|TYROSINE KINASE GROWTH FACTOR RECEPTOR|FLK1, MOUSE, HOMOLOG OF|VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR|VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2|Fetal liver kinase 1|Kinase insert domain receptor|Protein-tyrosine kinase receptor flk-1
• Uniprot ID
  Human(P35968), Mouse(P35918), Rat(O08775)
• Entrez GeneID
  Human(3791), Mouse(16542), Rat(25589)
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  VEGFR2   KDR1  
• Gene symbol
  KDR
• Short name
  VEGFR2 Antibody ( KDR1)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  VEGFR2 (antibody to-) ( KDR1)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6307
• Gene
  KDR
• Long gene name
  kinase insert domain receptor
• Synonyms gene name
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
• Synonyms
  • FLK1
  • VEGFR
  • VEGFR2
  • CD309
• Synonyms name
  • vascular endothelial growth factor receptor 2
  • fetal liver kinase 1
• GenBank acession
  • AF035121
• Locus
  4q12
• Discovery year
  1991-07-10
• Entrez gene record
  3791
• Pubmed identfication
  • 1417831
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • I-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000128734
• Locus Specific Databases
  • The Globin Gene Server
  • LRG_1198

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products