VDAC1 Antibody

• Catalog number
  bs-1461R
• Price
  Please ask
• Size
  0.1ml

• Long name
  VDAC1 Primary Polyclonal Antibody
• Also known as
  VDAC1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  VDAC
• Specificity
  This is a highly specific antibody against VDAC. May detect VDAC2 due to sequence similarity
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  95-130/283
• Subcellular location
  Mitochondrion
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human VDAC1
• Gene ID number
  7416
• Swiss Prot
  P21796
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PORIN; VDAC-1; Voltage-dependent anion-selective channel protein 1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; VDAC1; VDAC
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  VDAC1  
• Gene symbol
  VDAC1
• Short name
  Anti-VDAC
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  VDAC1 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  voltage-dependent anion channel 1, PORIN and VDAC-1, VDAC1 and IDBG-240337 and ENSG00000213585 and 7416, porin activity, nuclei, Vdac1 and IDBG-171107 and ENSMUSG00000020402 and 22333, VDAC1 and IDBG-645740 and ENSBTAG00000013113 and 282119

Gene info

• Identity
  HGNC:12669
• Gene
  VDAC1
• Long gene name
  voltage dependent anion channel 1
• Synonyms
  • MGC111064
  • PORIN
• Locus
  5q31.1
• Discovery year
  1993-11-02
• Entrez gene record
  7416
• Pubmed identfication
  • 7517385
• Classification
  • Voltage dependent anion channels
• VEGA ID
  OTTHUMG00000129118

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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