VDAC1 Antibody
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Catalog numberbs-1461R
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PricePlease ask
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Size0.1ml
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Long nameVDAC1 Primary Polyclonal Antibody
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Also known asVDAC1 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenVDAC
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SpecificityThis is a highly specific antibody against VDAC. May detect VDAC2 due to sequence similarity
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range95-130/283
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Subcellular locationMitochondrion
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human VDAC1
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Gene ID number7416
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Swiss ProtP21796
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenForms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesPORIN; VDAC-1; Voltage-dependent anion-selective channel protein 1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; VDAC1; VDAC
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolVDAC1
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Short nameAnti-VDAC
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameVDAC1 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetvoltage-dependent anion channel 1, PORIN and VDAC-1, VDAC1 and IDBG-240337 and ENSG00000213585 and 7416, porin activity, nuclei, Vdac1 and IDBG-171107 and ENSMUSG00000020402 and 22333, VDAC1 and IDBG-645740 and ENSBTAG00000013113 and 282119
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Gene info
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Identity
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Gene
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Long gene namevoltage dependent anion channel 1
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Synonyms
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Locus
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Discovery year1993-11-02
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Entrez gene record
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Pubmed identfication
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Classification
- Voltage dependent anion channels
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data