Varlitinib for cell activation

Varlitinib for cell activation is available 2 times from Biovision labs

2656-5 | Varlitinib for cell activationsize: 5 mg | 254.98 USD

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2656-25 | Varlitinib for cell activationsize: 25 mg | 842.95 USD

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  • Description
    Varlitinib is a potent inhibitor of the epidermal growth factor receptor (EGFR) family with potential antineoplastic activity. Varlitinib selectively and reversibly binds to both EGFR (ErbB-1) and Her-2/neu (ErbB-2) and prevents their phosphorylation and activation, which may result in inhibition of the associated signal transduction pathways, inhibition of cellular proliferation and cell death. EGFR and Her-2 play important roles in cell proliferation and differentiation and are upregulated in various human tumor cell types. Due to the dual inhibition of both EGFR and Her-2, this agent may be therapeutically more effective than agents that inhibit EGFR or Her-2 alone. 
  • Peptide sequence
    N/A
  • CAS number
    845272-21-1
  • Molecular weight
    466.94
  • Category
    Biochemicals
  • Other name
    (R)-N4-(3-chloro-4-(thiazol-2-ylmethoxy)phenyl)-N6-(4-methyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine
  • Molecular formula
    C₂₂H₁₉ClN₆O₂S
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    Varlitinib for activation
  • Technique
    activation
  • Alternative name
    Varlitinib to measure cellular activation
  • Tissue
    cell
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