Valinomycin, Apoptosis Inducer

• Catalog number
  SIH-230-10MG
• Price
  Please ask
• Size
  10 mg

• Stock availabilitIn Stock
  In Stock
• CAS number
  2001-95-8
• Description
  Apoptosis Inducer
• Molecular weight
  1111,32 g/mol
• Primary research fields
  Cancer, Apoptosis
• Other name
  (3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29, 32,35-dodecone
• Product category
  Small Molecules
• Product type
  Inducer
• Chemical formula
  C54H90N6O18
• Origin
  Synthetic
• Purity pourcentage
  >98%
• Soluble in
  Soluble to 25 mM in DMSO and 25 mM in ethanol.
• Physical appearance
  White Solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed R68 - Possible risk of irreversible effects Hazard Phrases: H300-H310 Precautionary Phrases: P264-P280-P302 + P350-P310
• PubChem number
  5649
• Scientific context
  Valinomycin is a dodecadepsipeptide, and a member of a group of natural neutral ionophores. It is highly selective for potassium ions within the cell membrane (1). It functions as a potassium-specific transporter and facilitates the movement of potassium ions through lipid membranes down an electrochemical potential gradient (2).
• Bibliography
  1. Lars R., Jenkins A.T.A. (2007) Bioelectrochem. 70(2): 387-393. 2. Cammann K. (1985) Top Curr Chem. 128: 219-258.
• Release date
  16-May-2011
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of Valinomycin (SIH-230), a Induces loss of mitochondrial membrane potential. CAS #: 2001-95-8. Molecular Formula: C54H90N6O18. Molecular Weight: 1111.32 g/mol. Chemical structure of Valinomycin, a Induces loss of mitochondrial membrane potential (SIH-230). CAS # 2001-95-8. Molecular Formula: C54H90N6O18.
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  0.01
• Other related products
• Additional description
  This 1 is suited for programmed cell-death studies.

• Gene target
  Valinomycin   Inducer  
• Short name
  Valinomycin, Apoptosis Inducer
• Technique
  apoptosis, apoptosis pathway
• Alternative name
  Valinomycin, programmed cellular destruction Inducer
• Alternative technique
  celldeath

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