Uromodulin Antibody

• Catalog number
  bs-2189R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Uromodulin Primary Polyclonal Antibody
• Also known as
  Uromodulin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Uromodulin
• Specificity
  This is a highly specific antibody against Uromodulin.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  375-420/642
• Source
  KLH conjugated synthetic peptide derived from mouse Uromodulin
• Gene ID number
  22242
• Swiss Prot
  Q91X17
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability. May serve as a receptor for binding and endocytosis for cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelial (By similarity). Uromodulin, secreted form: Secreted into urine after proteolytically cleaveage. Into the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  THP; Urehd1; urehr4; Uromodulin; Tamm-Horsfall urinary glycoprotein; Umod
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Uromodulin  
• Gene symbol
  UMOD, UMODL1
• Short name
  Anti-Uromodulin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Uromodulin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12559
• Gene
  UMOD
• Long gene name
  uromodulin
• Synonyms gene name
  • uromodulin (uromucoid, Tamm-Horsfall glycoprotein)
• Synonyms name
  • Tamm-Horsfall glycoprotein
  • uromucoid
• GenBank acession
  • M17778
• Locus
  16p12.3
• Discovery year
  1992-07-27
• Entrez gene record
  7369
• Pubmed identfication
  • 8382593
• VEGA ID
  OTTHUMG00000131488

Gene info

• Identity
  HGNC:12560
• Gene
  UMODL1
• Long gene name
  uromodulin like 1
• Synonyms name
  • olfactorin
• Locus
  21q22.3
• Discovery year
  2000-05-17
• Entrez gene record
  89766
• Pubmed identfication
  • 16026467
• VEGA ID
  OTTHUMG00000086788

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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