STXBP1(Ser515) Antibody, ALEXA FLUOR 488

• Catalog number
  bs-5639R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  STXBP1(Ser515) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-STXBP1 Ser515 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  STXBP1 Ser515
• Specificity
  This is a highly specific antibody against STXBP1 Ser515.
• Modification
  Phosphorylation
• Modification Site
  Ser515
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human STXBP1 around the phosphorylation site of Ser515
• Gene ID Number
  6812
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Munc18 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Munc18 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions. Mutations in Munc18 can result in accumulations of acetylcholine and paralytic phenotype suggestive of a neurotransmitter release defect. Two Munc18 isoforms have recently been identified. Munc18-1 has been shown to be primarily expressed in brain, while Munc18-2 is expressed in most tissues.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  Stxbp1phospho S515; FLJ37475; hUNC 18; hUNC18; Munc 18 1; Munc 18; Munc 18a; Munc18 1; Munc18a; N Sec1; N-Sec1; Neuronal SEC1; NSec1; p67; Protein unc-18 homolog 1; Protein unc-18 homolog A; Rb sec1; RBSEC1; STX BP1; STXB1_HUMAN; STXBP 1; STXBP1; Syntaxin binding protein 1; Syntaxin-binding protein 1; Unc 18 1; UNC 18; Unc 18 homolog; Unc 18A; Unc-18A; Unc18 1; UNC18; Unc18 homolog; Unc18-1; Unc18A.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-STXBP1 Ser515 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  STXBP1   Ser515  
• Gene symbol
  STXBP1
• Short name
  Anti-STXBP1 Ser515
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  STXBP1(Ser515) Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  syntaxin binding protein 1, MUNC18-1 and NSEC1 and P67 and RBSEC1 and UNC18, STXBP1 and IDBG-86143 and ENSG00000136854 and 6812, protein N-terminus binding, Plasma membranes, Stxbp1 and IDBG-161623 and ENSMUSG00000026797 and 20910, STXBP1 and IDBG-638972 and ENSBTAG00000003525 and 282378

Gene info

• Identity
  HGNC:11444
• Gene
  STXBP1
• Long gene name
  syntaxin binding protein 1
• Synonyms
  • hUNC18
  • MUNC18-1
  • UNC18
  • rbSec1
  • nSec1
• Synonyms name
  • syntaxin-binding protein 1
• GenBank acession
  • AF004563
• Locus
  9q34.11
• Discovery year
  1996-12-27
• Entrez gene record
  6812
• Pubmed identfication
  • 9545644
• RefSeq identity
  • NM_003165
• VEGA ID
  OTTHUMG00000020713

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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