UNC 1215 for cell activation

UNC 1215 for cell activation is available 2 times from Biovision labs

2252-1 | UNC 1215 for cell activationsize: 1 mg | 142.28 USD

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2252-5 | UNC 1215 for cell activationsize: 5 mg | 346.89 USD

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  • Description
    Cell-permeable. A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. It binds L3MBTL3 with a Kd value of 120 nM (IC₅₀ = 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. UNC1215 is > 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined.
  • Peptide sequence
    N/A
  • CAS number
    1415800-43-9
  • Molecular weight
    529.72
  • Category
    Biochemicals
  • Other name
    (2-​(Phenylamino)-​1,​4-​phenylene)bis((4-​(pyrrolidin-​1-​yl)piperidin-​1-​yl)methanone
  • Molecular formula
    C₃₂H₄₃N₅O₂
  • Physical appearance
    White to Off-white Solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (50 mM)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    24 months
  • Storage instructions
    Protect from light and moisture
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    UNC 1215 for activation
  • Technique
    activation
  • Alternative name
    UNC 1215 to measure cellular activation
  • Tissue
    cell
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