UBE2J2 Antibody

• Catalog number
  bs-8381R
• Price
  Please ask
• Size
  0.1ml

• Long name
  UBE2J2 Primary Polyclonal Antibody
• Also known as
  UBE2J2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  UBE2J2
• Specificity
  This is a highly specific antibody against UBE2J2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UBE2J2
• Gene ID number
  118424
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  NCUBE-2; NCUBE2; Non-canonical ubiquitin-conjugating enzyme 2; UB2J2_HUMAN; UBC6; UBC6 homolog; ube2j2; Ubiquitin-conjugating enzyme E2 J2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  UBE2J2  
• Gene symbol
  UBE2J2
• Short name
  Anti-UBE2J2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  UBE2J2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19268
• Gene
  UBE2J2
• Long gene name
  ubiquitin conjugating enzyme E2 J2
• Synonyms gene name
  • ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)
  • ubiquitin-conjugating enzyme E2, J2
• Synonyms
  • Ubc6p
  • NCUBE2
• GenBank acession
  • AF296658
• Locus
  1p36.33
• Discovery year
  2002-11-26
• Entrez gene record
  118424
• Pubmed identfication
  • 11278356
• RefSeq identity
  • NM_058167
• Classification
  • Ubiquitin conjugating enzymes E2
• VEGA ID
  OTTHUMG00000001911

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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