Tumor necrosis factor alpha TNF-α (78-96) (human) (AA: His-Thr-Ile-Ser-Arg-Ile-Ala-Val-Ser-Tyr-Gln-Thr-Lys-Val-Asn-Leu-Leu-Ser-Ala) (MW: 2101.45)

• Catalog number
  SP-89730-1
• Price
  Please ask
• Size
  1 mg

• Stock availability
  Available
• Category
  Bioactive peptides
• Antibody type
  N/A
• Antibody host
  N/A
• Antibody conjugate
  N/A
• Technical datasheet
  Contact Gentaur to request the datasheet or ask our specialists for more information.
• Notes
  The Tumor necrosis factor alpha TNF-α (78-96) (human) (AA: His-Thr-Ile-Ser-Arg-Ile-Ala-Val-Ser-Tyr-Gln-Thr-Lys-Val-Asn-Leu-Leu-Ser-Ala) (MW: 2101.45) is manufactured for Research Use Only or for diagnostics purposes.
• Other related products
• Description
  The Tumor necrosis factor alpha TNF-α (78-96) ( ) (AA: His-Thr-Ile-Ser-Arg-Ile-Ala-Val-Ser-Tyr-Gln-Thr-Lys-Val-Asn-Leu-Leu-Ser-Ala) (MW: 2101 45) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Gene
  Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.

• Gene target
  Tumor   necrosis   factor   alpha   TNF-α   78-96   His-Thr-Ile-Ser-Arg-Ile-Ala-Val-Ser-Tyr-Gln-Thr-Lys-Val-Asn-Leu-Leu-Ser-Ala   2101  
• Gene symbol
  TNF, IGHV5-78, IGHVII-78-1, TNFRSF1A, ZNF155, RNU6-78P, RRP7A, CXCL5, TNFRSF1B, APH1A
• Short name
  Tumor necrosis factor alpha TNF-α (78-96) ( ) (AA: His-Thr-Ile-Ser-Arg-Ile-Ala-Val-Ser-Tyr-Gln-Thr-Lys-Val-Asn-Leu-Leu-Ser-Ala) (MW: 2101 45)
• Label
  His
• Species
  Human, Humans
• Alternative name
  Tumor necrosis factor a tumor necrosis factor-α (78-96) (H. sapiens) (AA: histidine-L-threonine-L-isoleucine-L-serine-L-arginine-L-isoleucine-alanine-L-valine-L-serine-L-tyrosine-L-glutamine-L-threonine-L-lysine-L-valine-L-asparagine-L-leucine-L-leucine-L-serine-alanine) (MW: 2101.45)
• Alternative to gene target
  tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
• Tissue
  tumor

Gene info

• Identity
  HGNC:11892
• Gene
  TNF
• Long gene name
  tumor necrosis factor
• Synonyms gene
  • TNFA
• Synonyms gene name
  • tumor necrosis factor (TNF superfamily, member 2)
• Synonyms
  • TNFSF2
  • DIF
  • TNF-alpha
• Synonyms name
  • TNF superfamily, member 2
• GenBank acession
  • X02910
• Locus
  6p21.33
• Discovery year
  1986-01-01
• Entrez gene record
  7124
• Pubmed identfication
  • 2413547
  • 6392892
• Classification
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000031194

Gene info

• Identity
  HGNC:5660
• Gene
  IGHV5-78
• Long gene name
  immunoglobulin heavy variable 5-78 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable 5-78
  • immunoglobulin heavy variable 5-78 pseudogene
• GenBank acession
  • X92213
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28387
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151873

Gene info

• Identity
  HGNC:5691
• Gene
  IGHVII-78-1
• Long gene name
  immunoglobulin heavy variable (II)-78-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-78-1
  • immunoglobulin heavy variable (II)-78-1 pseudogene
• Synonyms
  • IGHV(II)-78-1
• GenBank acession
  • AB019437
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28356
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151863

Gene info

• Identity
  HGNC:11916
• Gene
  TNFRSF1A
• Long gene name
  TNF receptor superfamily member 1A
• Synonyms gene
  • TNFR1
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1A
• Synonyms
  • TNF-R
  • TNFAR
  • TNFR60
  • TNF-R-I
  • CD120a
  • TNF-R55
• GenBank acession
  • M75866
• Locus
  12p13.31
• Discovery year
  1991-01-15
• Entrez gene record
  7132
• Pubmed identfication
  • 1655358
  • 2158863
• RefSeq identity
  • NM_001065
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000168267
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_193

Gene info

• Identity
  HGNC:12940
• Gene
  ZNF155
• Long gene name
  zinc finger protein 155
• Synonyms gene name
  • zinc finger protein 155 (pHZ-96)
• Synonyms
  • pHZ-96
• GenBank acession
  • U09852
• Locus
  19q13.31
• Discovery year
  1994-03-16
• Entrez gene record
  7711
• Pubmed identfication
  • 7557990
• RefSeq identity
  • NM_003445
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000182215

Gene info

• Identity
  HGNC:42568
• Gene
  RNU6-78P
• Long gene name
  RNA, U6 small nuclear 78, pseudogene
• Synonyms gene
  • RNU6-78
• Synonyms gene name
  • RNA, U6 small nuclear 78
• Locus
  13q12.13
• Discovery year
  2011-08-08
• Entrez gene record
  100873778
• RefSeq identity
  • NR_046944

Gene info

• Identity
  HGNC:24286
• Gene
  RRP7A
• Long gene name
  ribosomal RNA processing 7 homolog A
• Synonyms gene name
  • ribosomal RNA processing 7 homolog A (S. cerevisiae)
• Synonyms
  • CGI-96
  • Rrp7
• GenBank acession
  • BC035992
• Locus
  22q13.2
• Discovery year
  2008-07-25
• Entrez gene record
  27341
• Pubmed identfication
  • 10810093
  • 12087473
• RefSeq identity
  • NM_015703
• Classification
  • UTPc subcomplex
  • Ribosomal biogenesis factors
• VEGA ID
  OTTHUMG00000150891

Gene info

• Identity
  HGNC:10642
• Gene
  CXCL5
• Long gene name
  C-X-C motif chemokine ligand 5
• Synonyms gene
  • SCYB5
• Synonyms gene name
  • small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78)
  • chemokine (C-X-C motif) ligand 5
• Synonyms
  • ENA-78
• GenBank acession
  • X78686
• Locus
  4q13.3
• Discovery year
  1996-09-03
• Entrez gene record
  6374
• Pubmed identfication
  • 7929219
• RefSeq identity
  • NM_002994
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000160871

Gene info

• Identity
  HGNC:11917
• Gene
  TNFRSF1B
• Long gene name
  TNF receptor superfamily member 1B
• Synonyms gene
  • TNFR2
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1B
• Synonyms
  • TNFBR
  • TNFR80
  • TNF-R75
  • TNF-R-II
  • p75
  • CD120b
• GenBank acession
  • M32315
• Locus
  1p36.22
• Discovery year
  1991-01-15
• Entrez gene record
  7133
• Pubmed identfication
  • 2158863
  • 8702885
• RefSeq identity
  • NM_001066
• Classification
  • CD molecules
  • MicroRNA protein coding host genes
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000001829

Gene info

• Identity
  HGNC:29509
• Gene
  APH1A
• Long gene name
  aph-1 homolog A, gamma-secretase subunit
• Synonyms gene name
  • anterior pharynx defective 1 homolog A (C. elegans)
  • APH1A gamma secretase subunit
• Synonyms
  • APH-1A
  • CGI-78
• GenBank acession
  • AF151835
• Locus
  1q21.2
• Discovery year
  2005-02-08
• Entrez gene record
  51107
• Pubmed identfication
  • 10810093
  • 12110170
• RefSeq identity
  • NM_016022
• VEGA ID
  OTTHUMG00000012545

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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