TSG101 Antibody

• Catalog number
  F47990-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TSG101
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the TSG101 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TSG101 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q99816
• Purity
  Purified
• Description
  TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
• Immunogen
  A portion of amino acids 340-370 from the human protein was used as the immunogen for this TSG101 antibody.
• Storage
  Aliquot the TSG101 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TSG101  
• Gene symbol
  TSG101
• Short name
  Anti-TSG101
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to TSG101
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:15971
• Gene
  TSG101
• Long gene name
  tumor susceptibility 101
• Synonyms gene
  • TSG10
• Synonyms gene name
  • tumor susceptibility gene 10
  • tumor susceptibility gene 101
• Synonyms
  • VPS23
• GenBank acession
  • U82130
• Locus
  11p15.1
• Discovery year
  2001-07-20
• Entrez gene record
  7251
• Pubmed identfication
  • 9019400
  • 9241264
• RefSeq identity
  • NM_006292
• Classification
  • ESCRT-I
• VEGA ID
  OTTHUMG00000167725

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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