TRPM7 Antibody (CHAK1)

• Catalog number
  F40171-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS pH 7.4 with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TRPM7 (CHAK1)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
• Notes
  Titration of the TRPM7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TRPM7 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q96QT4
• Purity
  Purified
• Description
  TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM]
• Immunogen
  A portion of amino acids 1821-1850 from the human protein was used as the immunogen for this TRPM7 antibody.
• Storage
  Aliquot the TRPM7 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRPM7   CHAK1  
• Gene symbol
  TRPM7
• Short name
  Anti-TRPM7 (CHAK1)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to TRPM7 (CHAK1)
• Alternative technique
  antibodies
• Alternative to gene target
  transient receptor potential cation channel, subfamily M, member 7, TRPM7 and IDBG-11807 and ENSG00000092439 and 54822, transferase activity, Plasma membranes, Trpm7 and IDBG-204376 and ENSMUSG00000027365 and 58800, TRPM7 and IDBG-646663 and ENSBTAG00000031165 and 514642

Gene info

• Identity
  HGNC:17994
• Gene
  TRPM7
• Long gene name
  transient receptor potential cation channel subfamily M member 7
• Synonyms gene name
  • transient receptor potential cation channel, subfamily M, member 7
• Synonyms
  • CHAK1
  • LTRPC7
  • TRP-PLIK
• GenBank acession
  • AF346629
• Locus
  15q21.2
• Discovery year
  2002-01-11
• Entrez gene record
  54822
• Pubmed identfication
  • 11161216
  • 11385574
  • 16382100
• RefSeq identity
  • NM_017672
• Classification
  • Transient receptor potential cation channels
• VEGA ID
  OTTHUMG00000172449
• Locus Specific Databases
  • LRG_1192

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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