TRPM2 Antibody

  • Catalog number
    PA2231
  • Price
    Please ask
  • Size
    0,1 mg
  • Target antigen
    TRPM2
  • Clonality
    Polyclonal antibody
  • Clone
    Polyclonal antibody
  • Raised in
    rabbit
  • Type of the antibody
    IgG polyclonal antibody
  • Product form
    freeze-dried
  • Reacts with species
    human, mouse, rat
  • Analyses
    WB,IHC-P
  • Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human TRPM2(91-106aa CGYTHEQHLEEATKPH), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.
  • Product configuration
    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
  • Purification
    Immunogen affinity purified.
  • Solubilization
    The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
  • Storage condtions
    Keep the TRPM2 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
  • Tips
    The TRPM2 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
  • Background
    Transient receptor potential cation channel subfamily M member 2, also known as TRPM2 is a protein that in humans is encoded by the TRPM2 gene. Using a cosmid/BAC contig, this gene is mapped to chromosome 21q22.3. The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
  • Related articles
    1. Du, J., Xie, J., Yue, L. Intracellular calcium activates TRPM2 and its alternative spliced isoforms. Proc. Nat. Acad. Sci. 106: 7239-7244, 2009. 2. Farooqi, A. A., Javeed, M. K., Javed, Z., Riaz, A. M., Mukhtar, S., Minhaj, S., Abbas, S., Bhatti, S. TRPM channels: same ballpark, different players, and different rules in immunogenetics. Immunogenetics 63: 773-787, 2011. 3. McQuillin, A., Bass, N. J., Kalsi, G., Lawrence, J., Puri, V., Choudhury, K., Detera-Wadleigh, S. D., Curtis, D., Gurling, H. M. D. Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3. Molec. Psychiat. 11: 134-142, 2006.
  • Gene Name
    TRPM2
  • Protein Name
    Transient receptor potential cation channel subfamily M member 2
  • Gene Full Name
    transient receptor potential cation channel, subfamily M, member 2
  • Synonyms
    EREG 1 antibody|EREG1 antibody|Estrogen responsive element associated gene 1 antibody|Estrogen responsive element associated gene 1 protein antibody|Estrogen-responsive element-associated gene 1 protein antibody|KNP 3 antibody|KNP3 antibody|Long transient receptor potential channel 2 antibody|LTRPC 2 antibody|LTrpC-2 antibody|LTRPC2 antibody|MGC133383 antibody|NUDT9H antibody|NUDT9L1 antibody|putative Ca2+ channel protein antibody|transient receptor potential cation channel subfamily M member 2 antibody|Transient receptor potential channel 7 antibody|TRPC 7 antibody|TRPC7 antibody|TRPM 2 antibody|Trpm2 antibody|TRPM2_HUMAN antibody
  • Uniprot ID
    O94759
  • Properties
    If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    TRPM2  
  • Gene symbol
    TRPM2-AS, TRPM2
  • Short name
    TRPM2 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    TRPM2 (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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