TRIM / TRAT1 monoclonal antibody
-
Catalog number
1P-344-C100
-
Price
Please ask
-
Size
100ug
-
-
Long name
Mouse Monoclonal Antibody against Human TRIM / TRAT1, Clone: TRIM-04
-
Antigen
TRIM
-
Species reactivity
Human (Homo sapiens)
-
Negative species reactivity
Mouse
-
Clonality
Monoclonal Antibody (Mab)
-
Clone
TRIM-04
-
Applications
FC, IP, WB
-
Immunogen
Recombinant intracellular domain (aa 29-186) of human TRIM.
-
Format conjugation
PE
-
Specificity
The antibody TRIM-04 reacts with T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells.
-
Research area
Adaptor Proteins (Human), Adaptor Proteins
-
Concentration
0.1 mg/ml
-
Storage buffer
The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
-
Shipping and storage
Mouse Monoclonal Antibody against Human TRIM / TRAT1, Clone: TRIM-04 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
-
Background
TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.
-
Purity
> 95% (by SDS-PAGE)
-
Purification method
Purified by affinity chromatography
-
-
References
*Kirchgessner H, Dietrich J, Scherer J, Isomaki P, Korinek V, Hilgert I, Bruyns E, Leo A, Cope AP, Schraven B.: The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain. J Exp Med. 2001 Jun 4;193(11):1269-84. _x000D_
-
Properties
If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
French translation
anticorps
-
Gene target
-
Gene symbol
TRAT1
-
Short name
Anti-TRIM / TRAT1 Mab
-
Technique
Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
-
Host
Mouse (Mus musculus)
-
Isotype
IgG2a
-
Alternative name
Mouse Monoclonal to TRIM / TRAT1
-
Alternative technique
antibodies
-
Alternative to gene target
T cell receptor associated transmembrane adaptor 1, TRAT1 and IDBG-49131 and ENSG00000163519 and 50852, transmembrane receptor protein tyrosine kinase adaptor activity, Plasma membranes, Trat1 and IDBG-164471 and ENSMUSG00000030775 and 77647, BT.53544 and IDBG-632053 and ENSBTAG00000000183 and 614942
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
