Traut's Reagent
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Catalog number2330-1000
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PricePlease ask
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Size1 g
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Alternative_name2-Iminothiolane HCl; 2-IT; Dihydro-2-(3H)-thiophenimine hydrochloride; Dihydro-2-(3H)-thiophenimine HCl
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DescriptionKEY FEATURES & APPLICATIONS: • Water-soluble • Adds a 5-atom spacer arm (8.1 Å) to minimize steric hindrance • The spacer is cleavable at the disulfide bond with reducing agent, such as DTT, TCEP, etc. • Commonly used to convert primary amines into sulfhydryl groups in a one-step process is called thiolation • Amine reactive at pH 7-10 and is also an effective thiolation reagent for polysaccharides • Useful RNA-protein crosslinking reagent.
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CAS Number4781-83-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₄H₇NS•HCl
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Molecular Weight137.63
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Cell PermeableNo
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Purity≥90% by NMR
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SolubilitiesH2O or aqueous buffers
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HandlingProtect from moisture
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Tag LineA useful reagent for converting primary amine functional groups into free sulfhydryl groups
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Storage Condition+4 ̊C
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Shipping ConditionGel Pack
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Shelf Life36 months
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MDL NumberMFCD00039013
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PubChem CID13166855
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SMILESC1CC(=N)SC1.Cl
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InChiInChI=1S/C4H7NS.ClH/c5-4-2-1-3-6-4;/h5H,1-3H2;1H
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InChi KeyATGUDZODTABURZ-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameTraut's Reagent
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Alternative nameTraut's Reagent
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