Transmembrane Protein 30A Antibody

  • Catalog number
    bs-16576R
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    Transmembrane Protein 30A Antibody
  • Also known as
    Transmembrane Protein 30A Antibody
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Target Antigen
    Transmembrane protein 30A
  • Specificity
    This is a highly specific antibody against Transmembrane protein 30A.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    300-330/361
  • Subcellular location
    Extracellular
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Transmembrane protein 30A
  • Gene ID number
    55754
  • Swiss Prot
    Q9NV96
  • Tested Applications
    WB
  • Recommended dilutions
    WB(1:100-1000)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes. Involved in uptake of platelet-activating factor (PAF), synthetic drug alkylphospholipid edelfosine, and, probably in association with ATP8B1, of perifosine. Also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    CDC50A; C6orf67; Cell cycle control protein 50A; P4-ATPase flippase complex beta subunit TMEM30A; Transmembrane protein 30A; TMEM30A
  • Properties
    If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    MIR30A, ADAM1A
  • Short name
    Anti-Transmembrane protein 30A
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Isotype
    Immunoglobulin G (IgG)
  • Alternative name
    Transmembrane Protein 30A Antibody
  • Alternative technique
    antibodies
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    ADAM metallopeptidase domain 1A (pseudogene)
  • Synonyms gene
  • Synonyms gene name
    • a disintegrin and metalloproteinase domain 1 (fertilin alpha) pseudogene
    • ADAM metallopeptidase domain 1, pseudogene
    • ADAM metallopeptidase domain 1A, pseudogene
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    1998-12-01
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • ADAM metallopeptidase domain containing
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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