Transmembrane Protein 30A Antibody
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Catalog numberbs-16576R
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PricePlease ask
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Size0.1ml
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Long nameTransmembrane Protein 30A Antibody
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Also known asTransmembrane Protein 30A Antibody
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenTransmembrane protein 30A
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SpecificityThis is a highly specific antibody against Transmembrane protein 30A.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range300-330/361
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Transmembrane protein 30A
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Gene ID number55754
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Swiss ProtQ9NV96
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Tested ApplicationsWB
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Recommended dilutionsWB(1:100-1000)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenAccessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes. Involved in uptake of platelet-activating factor (PAF), synthetic drug alkylphospholipid edelfosine, and, probably in association with ATP8B1, of perifosine. Also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesCDC50A; C6orf67; Cell cycle control protein 50A; P4-ATPase flippase complex beta subunit TMEM30A; Transmembrane protein 30A; TMEM30A
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMIR30A, ADAM1A
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Short nameAnti-Transmembrane protein 30A
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameTransmembrane Protein 30A Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namemicroRNA 30a
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR30 family
Gene info
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Identity
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Gene
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Long gene nameADAM metallopeptidase domain 1A (pseudogene)
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Synonyms gene
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Synonyms gene name
- a disintegrin and metalloproteinase domain 1 (fertilin alpha) pseudogene
- ADAM metallopeptidase domain 1, pseudogene
- ADAM metallopeptidase domain 1A, pseudogene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-12-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ADAM metallopeptidase domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data