Tranilast

  • Catalog number
    1876-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid; SB 252218
  • Description
    Cell-permeable. A potent angiogenesis inhibitor. Inhibits VEGF-induced angiogenetic activities. Displays anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-β1-induced proliferation and migration of vascular medial smooth muscle cells.
  • CAS Number
    53902-12-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₈H₁₇NO₅
  • Molecular Weight
    327.33
  • Cell Permeable
    Yes
  • Purity
    ≥98%
  • Solubilities
    DMSO (100 mM)
  • Handling
    Protect from air and light
  • Tag Line
    A potent angiogenesis inhibitor.
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD00864787
  • PubChem CID
    5282230
  • SMILES
    COC1=C(C=C(C=C1)C=CC(=O)NC2=CC=CC=C2C(=O)O)OC
  • InChi
    InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+
  • InChi Key
    NZHGWWWHIYHZNX-CSKARUKUSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Tranilast
  • Alternative name
    Tranilast
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