Synonyms Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF
Alternates names Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF
Taglines Stimulates the proliferation and maturation of megakaryocytes
NCBI Gene ID #. 81811
NCBI Gene Symbol TPO
Gene Source Rat
Accession # P49745
Source E. Coli
Endotoxin Level<0.1 ng/μg of protein (
Activity (Specifications/test method) Determined by its ability to stimulate the proliferation of human MO7e cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10^6 units/mg.
Biological activity Determined by its ability to stimulate the proliferation of human MO7e cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10^6 units/mg.
Molecular Weight 18.7 kDa
Storage Temp. -20°C
Shipping Gel Pack
Shelf Life 1 year
Appearance Lyophilized powder
Physical form description Sterile filtered through a 0.2 micron filter. Lyophilized from Sodium Citrate, pH 4.5
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
About Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name Rattus norvegicus
Additional source Recombinants or rec. proteins
Short name TPO, recombinant
Alternative name TPO, rat recombinant
Alternative technique rec