TP63 (603CT12.4.3) Monoclonal Antibody

• Catalog number
  bsm-51191M
• Price
  Please ask
• Size
  0.1ml

• Long name
  TP63 (603CT12.4.3) Monoclonal Antibody
• Also known as
  TP63 (603CT12.4.3) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TP63
• Specificity
  This is a highly specific antibody against TP63.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  603CT12.4.3
• Source
  This TP63 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 651-680 amino acids from human TP63.
• Gene ID number
  8626
• Swiss Prot
  Q9H3D4
• Tested Applications
  WB
• Recommended dilutions
  WB(1:200~1600)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
• Purification method
  Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B); Tumor protein 63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor KET; Transformation-related protein 63; TP63; Tumor protein p73-like
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  TP63   603CT12   Monoclonal  
• Gene symbol
  TP63
• Short name
  Anti-TP63
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgM
• Alternative name
  TP63 (603CT12.4.3) Monoclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  tumor protein p63, AIS and B(p51A) and B(p51B) and EEC3 and KET and LMS and NBP and OFC8 and p40 and p51 and p53CP and p63 and p73H and p73L and RHS and SHFM4 and TP53CP and TP53L and TP73L, TP63 and IDBG-69487 and ENSG00000073282 and 8626, WW domain binding, nuclei, Trp63 and IDBG-150133 and ENSMUSG00000022510 and 22061, TP63 and IDBG-634533 and ENSBTAG00000015460 and 615335

Gene info

• Identity
  HGNC:15979
• Gene
  TP63
• Long gene name
  tumor protein p63
• Synonyms gene
  • TP73L
  • TP53L
  • TP53CP
• Synonyms gene name
  • tumor protein p73-like
  • tumor protein p53-like
  • tumor protein p53-competing protein
• Synonyms
  • p51
  • SHFM4
  • EEC3
  • p63
  • p73L
  • OFC8
  • KET
  • p73H
  • NBP
  • p53CP
• GenBank acession
  • AB010153
• Locus
  3q28
• Discovery year
  2002-04-18
• Entrez gene record
  8626
• Pubmed identfication
  • 9774969
  • 9662378
  • 11181441
  • 11181451
• RefSeq identity
  • NM_003722
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000156313
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_428

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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