ToxOut™ Rapid Endotoxin Removal Kit

  • Catalog number
    K2501-5
  • Price
    Please ask
  • Size
    5 columns
  • Description
    Quickly and effectively eliminate endotoxins to < 0.05 EU/ml in solutions containing proteins or pharmacologically important components. Endotoxin is the lipopolysaccharide (LPS) complex located in the outer membrane of gram-negative bacteria. A single E.coli bacterium contains ~2 million LPS molecules (2 – 20 fg/cell). During experimental procedures, large amount of endotoxins are shed and can easily contaminate labware, buffers and downstream products. In vitro, endotoxin causes a variety of problems in cell-based research. In vivo, endotoxin may cause various side effects, including inflammatory response, organ failure or septic shock in host organisms. Therefore, it is critical to remove endotoxin from samples and products. BioVision‘s ToxOutTM Rapid Endotoxin Removal Kit can quickly and effectively eliminate endotoxins to < 0.05 EU/ml in solutions containing proteins or pharmacologically important components via the immobilized polymyxin B, which is known for capturing endotoxin and preventing toxic effects.
  • Product Highlights
    • High Binding Capacity: up to 9 x 108 EU/ml resin • High Sample Recovery: ~90% recovery with protein solution samples • Column Content: 5 x 100 µl ToxOutTM Rapid Endotoxin Removal Agarose (Cat. No. 7941-5) • Resin Content: affinity matrix of polymyxin B, supplied as 50% slurry in 20% ethanol • Each column can be reused up to 5 times • Rapid removal: only require 5 minutes for each removal cycle
  • Storage Temp
    4°C Do not freeze
  • Shipping
    gel pack
  • Shelf Life
    12 months
  • Notes
    For research use only. Not to be used for human or animal treatment or consumption.
  • Gene target
  • Short name
    ToxOut™ Rapid Endotoxin Removal Kit
  • Alternative name
    ToxOut™ Rapid Endotoxin Removal reagent
  • Alternative technique
    kits
  • Alternative to gene target
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
MeSH Data
  • Name
  • Concept
    Scope note: Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals.
  • Tree numbers
    • E01.370.225.124.470
    • E01.370.225.875.150.570
    • E05.091.570
    • E05.200.124.470
    • E05.200.875.150.570
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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