Torsin A Antibody

• Catalog number
  bs-11490R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Torsin A Primary Polyclonal Antibody
• Also known as
  Torsin A PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Torsin A
• Specificity
  This is a highly specific antibody against Torsin A.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Torsin A
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  A mutation of the DYT1 gene, which codes for TorsinA, has been identified as the cause of one form of autosomal dominantly inherited dystonia. Early-onset torsion dystonia is a movement disorder, characterized by twisting muscle contractures, that begins in childhood. Symptoms are believed to result from altered neuronal communication in the basal ganglia. TorsinA comprises 332 amino acids. TorsinA is widely expressed throughout the mouse central nervous system and is detected in the majority of neurons in nearly all regions. The proteins display cytoplasmic distribution, although in some types of neurons localization is perinuclear. TorsinA often performs chaperone-like functions that assist in the assembly, operation, or dis-assembly of protein complexes. The gene which encodes TorsinA has high homology to three additional mammalian genes and a nematode gene and distal similarity to the family of heat-shock proteins and the Clp protease family. The gene which encodes TorsinA maps to human chromosome 9q34.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  DQ2; Dystonia 1; Dystonia 1 protein; Dyt1; Tor1a; Torsin A; Torsin family 1 member A; TOR1A_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Torsin  
• Gene symbol
  TOR1A, TOR2A, TOR3A
• Short name
  Anti-Torsin A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Torsin A Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3098
• Gene
  TOR1A
• Long gene name
  torsin family 1 member A
• Synonyms gene
  • DYT1
• Synonyms gene name
  • dystonia 1, torsion (autosomal dominant; torsin A)
  • torsin family 1, member A (torsin A)
• Synonyms
  • DQ2
• Synonyms name
  • torsin A
• GenBank acession
  • AF007871
• Locus
  9q34.11
• Discovery year
  1987-09-11
• Entrez gene record
  1861
• Pubmed identfication
  • 10644435
• RefSeq identity
  • NM_000113
• Classification
  • Torsins
• VEGA ID
  OTTHUMG00000020794
• Locus Specific Databases
  • LRG_1029

Gene info

• Identity
  HGNC:11996
• Gene
  TOR2A
• Long gene name
  torsin family 2 member A
• Synonyms gene name
  • torsin family 2, member A
• Synonyms
  • FLJ14771
  • TORP1
• GenBank acession
  • AA873275
• Locus
  9q34.11
• Discovery year
  2000-02-17
• Entrez gene record
  27433
• Pubmed identfication
  • 10644435
• RefSeq identity
  • NM_130459
• Classification
  • Torsins
• VEGA ID
  OTTHUMG00000020706

Gene info

• Identity
  HGNC:11997
• Gene
  TOR3A
• Long gene name
  torsin family 3 member A
• Synonyms gene
  • ADIR
• Synonyms gene name
  • ATP-dependant interferon responsive
  • torsin family 3, member A
• Synonyms
  • FLJ22345
  • ADIR2
• GenBank acession
  • BC001085
• Locus
  1q25.2
• Discovery year
  2000-02-17
• Entrez gene record
  64222
• Pubmed identfication
  • 10644435
• RefSeq identity
  • NM_022371
• Classification
  • Torsins
  • Minor histocompatibility antigens
• VEGA ID
  OTTHUMG00000035077

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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