mTOR, Mammalian target of Rapamycin (monoclonal)

• Catalog number
  AS16 4014
• Price
  Please ask
• Size
  100 µg

• Available ordering format
  Liquid
• Immunogen
  KLH-conjugated synthetic peptide to residues near the carboxy-terminal sequence of human VEGF Receptor 2. UniProt: Human: P42345, Rat: P42346, Mouse: Q9JLN9
• Raised in
  Mouse
• Clonality
  Monoclonal
• Clone
  215Q18, IgG1
• Purification
  Protein A/G purified.
• How to reconstitute
  See included datasheet or contact our support service
• Storage condition
  Store at -20 °C.
• Verified applications
  Western blot (WB)
• Connected products
  anti-mouse secondary antibodies
• Recommended dilutions for use
  1:1000 starting dilution (WB). The optimal antibody concentration should be determined for each specific application by the end user.
• Molecular weight expected аpparent
  280 kDa
• Verified reactivity
  Human, Mouse, Rat
• Possible reactivity
  to be determined
• No reactivity
  No confirmed exceptions from predicted reactivity known at the moment.
• Supplementary information
  Contact Gentaur support center at [email protected]
• References
  To be added when available, antibody released in November 2016.
• Scientific context
  Mammalian target of Rapamycin is an important modulator of cell growth and protein synthesis and a ia an serine/threonine kinase. mTOR is involved in cancer and neurite plasticity. This protein plays an important role in mediating phosphoinositide 3-kinase (PI3 kinase) and Akt/PKB signals for cell growth, proliferation, and protein translation via ribosomal S6 kinase (S6Ks) and translation regulator eIF4E-binding protein 1.
• Notes
  Provided in phosphate buffered saline, pH 7.3, 50% glycerol with 1.0 mg/ml BSA and 0.05% sodium azide.
• Protein number
  Q9JLN9,P42346,P42345
• TAIR number
  Refer to NCBI
• Hyperlink
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

• Gene target
  mTOR   Mammalian   Rapamycin   monoclonal  
• Short name
  mTOR, Mammalian of Rapamycin (monoclonal)
• Technique
  Monoclonals or monoclonal antibodies
• Alternative name
  Mammalian target on rapamycin, Mammalian target on Rapamycin (monoclonal)
• Alternative to gene target
  mechanistic target of rapamycin (serine/threonine kinase), FRAP and FRAP1 and FRAP2 and RAFT1 and RAPT1, MTOR and IDBG-89258 and ENSG00000198793 and 2475, transferase activity, nuclei, Mtor and IDBG-204403 and ENSMUSG00000028991 and 56717, MTOR and IDBG-632731 and ENSBTAG00000015325 and 100139219

Similar products