TNFRSF14/HVEM Antibody, Biotin Conjugated

• Catalog number
  bs-2457R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  TNFRSF14/HVEM Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TNFRSF14/HVEM
• Specificity
  This is a highly specific antibody against TNFRSF14/HVEM.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human TNFRSF14
• Gene ID number
  8764
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  TNFRSF14 is a type I membrane protein belonging to the TNF receptor superfamily. This receptor mediates herpes virus entry into cells during infection. TNFRSF14 is able to inhibit the proliferation, activation, and cytokine production of T cells. It has an extracellular domain containing several cysteine-rich repeats and a short cytoplasmic region containing a TRAF (TNF receptor-associated factor) interaction domain. The extracellular domain of TNFRSF14 interacts with the herpes simplex virus envelope glycoprotein D. TNFRSF14 binds two cellular ligands: lymphotoxin alpha and LIGHT. LIGHT is a transmembrane protein expressed and shed from the surface of activated T cells, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes. The LIGHT:TNFRSF14 interaction controls immune response functions by cell death induction as well as cell activation. TNFRSF14 is expressed by peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  Tumor necrosis factor receptor superfamily member 14; HVEML; ATAR; CD258; CD258 antigen; CD40 like protein precursor; Herpesvirus entry mediator A; Herpesvirus entry mediator; Herpesvirus entry mediator ligand; HVEA; HVEM; HVEM L; HVEML; LIGHT; LIGHTR; TNFSF 14; TR2; Tumor necrosis factor receptor like gene2; TNR14_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  TNFRSF14/HVEM   Conjugated  
• Gene symbol
  TNFRSF14, TNFRSF14-AS1, TNFSF14
• Short name
  Anti-TNFRSF14/HVEM
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-TNFRSF14/HVEM PAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  tumor necrosis factor receptor superfamily, member 14, ATAR and CD270 and HVEA and HVEM and LIGHTR and TR2, TNFRSF14 and IDBG-86399 and ENSG00000157873 and 8764, ubiquitin protein ligase binding, Cell surfaces, Tnfrsf14 and IDBG-207237 and ENSMUSG00000042333 and 230979

Gene info

• Identity
  HGNC:11912
• Gene
  TNFRSF14
• Long gene name
  TNF receptor superfamily member 14
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
  • tumor necrosis factor receptor superfamily, member 14
• Synonyms
  • HVEM
  • ATAR
  • TR2
  • LIGHTR
  • HVEA
  • CD270
• Synonyms name
  • herpesvirus entry mediator
• GenBank acession
  • U70321
• Locus
  1p36.32
• Discovery year
  1998-12-04
• Entrez gene record
  8764
• Pubmed identfication
  • 8898196
  • 9162061
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000000792

Gene info

• Identity
  HGNC:26966
• Gene
  TNFRSF14-AS1
• Long gene name
  TNFRSF14 antisense RNA 1
• Synonyms
  • ENST00000416860.2
• Locus
  1p36.32
• Discovery year
  2017-04-27
• Entrez gene record
  115110
• Pubmed identfication
  • 28418905
• RefSeq identity
  • NR_037844
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:11930
• Gene
  TNFSF14
• Long gene name
  TNF superfamily member 14
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 14
• Synonyms
  • LIGHT
  • LTg
  • HVEM-L
  • CD258
• GenBank acession
  • AF036581
• Locus
  19p13.3
• Discovery year
  1998-12-04
• Entrez gene record
  8740
• Pubmed identfication
  • 9462508
• Classification
  • Tumor necrosis factor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000181835

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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