TMP 153 for cell activation

TMP 153 for cell activation is available 2 times from Biovision labs

B1181-50 | TMP-153 for cell activationsize: 50 mg | 687.78 USD

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B1181-10 | TMP-153 for cell activationsize: 10 mg | 217.56 USD

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  • Description
    TMP-153 is a selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) with IC₅₀ of 5 to 10 nM. It has potency to inhibit cholesterol esterification and reduces its influx into the plasma of rats and hamsters. TMP-153 is shown toxicity to prion infected neuronal (ScGT1) cells. It might have potential to increase caspase-3 activity and prostaglandin E2 production in ScGT1 Cells.
  • Peptide sequence
    N/A
  • CAS number
    128831-46-9
  • Molecular weight
    437.88
  • Category
    Biochemicals
  • Other name
    N-[4-(2-chlorophenyl)-6,7-dimethyl-3-quinolinyl]-N'-(2,4-difluorophenyl)-urea
  • Molecular formula
    C₂₄H₁₈ClF₂N₃O
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    N/A
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by TLC
  • Reconstitute instructions
    DMSO (~25 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    TMP-153 for activation
  • Technique
    activation
  • Alternative name
    TMP-153 to measure cellular activation
  • Tissue
    cell
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