ALAS-E Antibody, Cy7 Conjugated
-
Catalog numberbs-9516R-Cy7
-
PricePlease ask
-
Size0.1ml
-
-
Long nameALAS-E Polyclonal Antibody, Cy7 Conjugated
-
CategoryConjugated Primary Antibodies
-
ConjugationCy7
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenALAS-E
-
SpecificityThis is a highly specific antibody against ALAS-E.
-
ModificationUnmodified
-
Modification siteNone
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
SourceKLH conjugated synthetic peptide derived from human ALAS2/ALAS-E
-
Gene ID number212
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Antigen background5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
-
Excitation Emission743nm/767nm
-
Synonyms5-aminolevulinate synthase, erythroid-specic, mitochondrial; 5-aminolevulinic acid synthase; ALAS E; ALASE; ANH1; Delta aminolevulinate synthase; XLSA; 5 aminolevulinic acid synthase 2; 5-aminolevulinate synthase 2; 5-aminolevulinate synthase; 5-aminolevulinate synthase 2; Alas 2; ALAS; ALAS E; ALAS, erythroid; ALASE; Aminolevulinate, delta-, synthase 2; Aminolevulinic acid synthase 2, erythroid; ANH1; ASB; Delta ALA synthase 2; Delta ALA synthetase; Delta aminolevulinate synthase 2; Delta aminolevulinate synthase; Erythroid specic ALAS; FLJ93603; XLDPP; XLSA.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
-
Additional conjugationCy7
-
French translationanticorps
-
Gene target
-
Gene symbolHLA-E, ALAS1, SMC2, SNAR-E, IPCEF1, SNRPE, KLRC3, TLE4, IGHV1-69
-
Short nameAnti-ALAS-E
-
TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
-
IsotypeImmunoglobulin G (IgG)
-
LabelCy7
-
Alternative nameAnti-ALAS-E PAb Cy7
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namemajor histocompatibility complex, class I, E
-
GenBank acession
-
Locus
-
Discovery year1988-05-11
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- C1-set domain containing
- Histocompatibility complex
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene name5'-aminolevulinate synthase 1
-
Synonyms gene
-
Synonyms gene name
- aminolevulinate, delta-, synthase 1
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namestructural maintenance of chromosomes 2
-
Synonyms gene
-
Synonyms gene name
- SMC2 (structural maintenance of chromosomes 2, yeast)-like 1
- SMC2 structural maintenance of chromosomes 2-like 1 (yeast)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-02-22
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Condensin I subunits
- Condensin II subunits
- Structural maintenance of chromosomes proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesmall NF90 (ILF3) associated RNA E
-
Synonyms gene name
- small ILF3/NF90-associated RNA E
-
GenBank acession
-
Locus
-
Discovery year2008-07-03
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Small NF90 (ILF3) associated RNAs
Gene info
-
Identity
-
Gene
-
Long gene nameinteraction protein for cytohesin exchange factors 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2009-02-27
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Pleckstrin homology domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesmall nuclear ribonucleoprotein polypeptide E
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1988-11-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Sm spliceosomal proteins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namekiller cell lectin like receptor C3
-
Synonyms gene name
- killer cell lectin-like receptor subfamily C, member 3
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-01-16
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- C-type lectin domain containing
- Killer cell lectin like receptors
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameTLE family member 4, transcriptional corepressor
-
Synonyms gene name
- transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
- transducin like enhancer of split 4
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1993-12-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- WD repeat domain containing
- TLE family
- Wnt enhanceosome complex
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin heavy variable 1-69
-
Synonyms gene
-
GenBank acession
-
Locus
-
Discovery year2000-04-04
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Immunoglobulin heavy locus at 14q32.33
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data