ALAS-E Antibody, Cy7 Conjugated

  • Catalog number
    bs-9516R-Cy7
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    ALAS-E Polyclonal Antibody, Cy7 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy7
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    ALAS-E
  • Specificity
    This is a highly specific antibody against ALAS-E.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic peptide derived from human ALAS2/ALAS-E
  • Gene ID number
    212
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    743nm/767nm
  • Synonyms
    5-aminolevulinate synthase, erythroid-specic, mitochondrial; 5-aminolevulinic acid synthase; ALAS E; ALASE; ANH1; Delta aminolevulinate synthase; XLSA; 5 aminolevulinic acid synthase 2; 5-aminolevulinate synthase 2; 5-aminolevulinate synthase; 5-aminolevulinate synthase 2; Alas 2; ALAS; ALAS E; ALAS, erythroid; ALASE; Aminolevulinate, delta-, synthase 2; Aminolevulinic acid synthase 2, erythroid; ANH1; ASB; Delta ALA synthase 2; Delta ALA synthetase; Delta aminolevulinate synthase 2; Delta aminolevulinate synthase; Erythroid specic ALAS; FLJ93603; XLDPP; XLSA.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugated
    These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
  • Additional conjugation
    Cy7
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    HLA-E, ALAS1, SMC2, SNAR-E, IPCEF1, SNRPE, KLRC3, TLE4, IGHV1-69
  • Short name
    Anti-ALAS-E
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    Cy7
  • Alternative name
    Anti-ALAS-E PAb Cy7
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    structural maintenance of chromosomes 2
  • Synonyms gene
  • Synonyms gene name
    • SMC2 (structural maintenance of chromosomes 2, yeast)-like 1
    • SMC2 structural maintenance of chromosomes 2-like 1 (yeast)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-02-22
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Condensin I subunits
    • Condensin II subunits
    • Structural maintenance of chromosomes proteins
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    small NF90 (ILF3) associated RNA E
  • Synonyms gene name
    • small ILF3/NF90-associated RNA E
  • GenBank acession
  • Locus
  • Discovery year
    2008-07-03
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Small NF90 (ILF3) associated RNAs
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    killer cell lectin like receptor C3
  • Synonyms gene name
    • killer cell lectin-like receptor subfamily C, member 3
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-01-16
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • C-type lectin domain containing
    • Killer cell lectin like receptors
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    TLE family member 4, transcriptional corepressor
  • Synonyms gene name
    • transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
    • transducin like enhancer of split 4
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1993-12-20
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • WD repeat domain containing
    • TLE family
    • Wnt enhanceosome complex
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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