Titin Antibody, ALEXA FLUOR 488

• Catalog number
  bs-9861R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  Titin Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-Titin PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Titin
• Specificity
  This is a highly specific antibody against Titin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  2670-2703/34350
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Titin (Ig-like 15 domain)
• Gene ID Number
  7273
• Swiss Prot
  Q8WZ42
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  TMD; CMH9; CMD1G; CMPD4; EOMFC; HMERF; MYLK5; LGMD2J; Titin; Connectin; Rhabdomyosarcoma antigen MU-RMS-40.14; TTN
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Titin has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  Titin  
• Gene symbol
  TCAP, TTN, OBSCN
• Short name
  Anti-Titin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  Titin Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11610
• Gene
  TCAP
• Long gene name
  titin-cap
• Synonyms gene
  • LGMD2G
• Synonyms gene name
  • limb girdle muscular dystrophy 2G (autosomal recessive)
  • titin-cap (telethonin)
• Synonyms
  • T-cap
  • TELE
  • telethonin
  • CMD1N
• Synonyms name
  • 19 kDa sarcomeric protein
  • teneurin C-terminal associated peptide
• GenBank acession
  • AJ000491
• Locus
  17q12
• Discovery year
  2000-02-16
• Entrez gene record
  8557
• Pubmed identfication
  • 9350988
  • 9817758
• RefSeq identity
  • NM_003673
• VEGA ID
  OTTHUMG00000133215
• Locus Specific Databases
  • Leiden Muscular Dystrophy Pages
  • Leiden Muscular Dystrophy pages
  • LRG_210

Gene info

• Identity
  HGNC:12403
• Gene
  TTN
• Long gene name
  titin
• Synonyms gene
  • CMD1G
• Synonyms gene name
  • cardiomyopathy, dilated 1G (autosomal dominant)
• Synonyms
  • CMPD4
  • FLJ32040
  • TMD
  • CMH9
  • LGMD2J
  • MYLK5
• GenBank acession
  • X90568
• Locus
  2q31.2
• Discovery year
  1991-06-07
• Entrez gene record
  7273
• Pubmed identfication
  • 2129545
  • 10051295
• RefSeq identity
  • NM_133378
• Classification
  • Myosin light chain kinase family
  • I-set domain containing
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000154448
• Locus Specific Databases
  • FHC Mutation Database
  • TTN @ LOVD
  • Leiden Muscular Dystrophy pages
  • LRG_391

Gene info

• Identity
  HGNC:15719
• Gene
  OBSCN
• Long gene name
  obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
• Synonyms
  • KIAA1556
  • UNC89
  • KIAA1639
  • ARHGEF30
• GenBank acession
  • AJ002535
• Locus
  1q42.13
• Discovery year
  2001-05-21
• Entrez gene record
  84033
• Pubmed identfication
  • 11448995
  • 11814696
• RefSeq identity
  • NM_052843
• Classification
  • Myosin light chain kinase family
  • I-set domain containing
  • Dbl family Rho GEFs
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000039772
• Locus Specific Databases
  • LRG_412

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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