TIF1 gamma Antibody

• Catalog number
  bs-3582R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TIF1 gamma Primary Polyclonal Antibody
• Also known as
  TIF1 gamma PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  T1 gamma
• Specificity
  This is a highly specific antibody against T1 gamma.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  980-1030/1127
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TIF1 gamma
• Gene ID number
  51592
• Swiss Prot
  Q9UPN9
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ECTO; PTC7; RFG7; TF1G; TIF1G; TIFGAMMA; TIF1GAMMA; E3 ubiquitin-protein ligase TRIM33; Ectodermin homolog; RET-fused gene 7 protein; Protein Rfg7; Transcription intermediary factor 1-gamma; TIF1-gamma; Tripartite motif-containing protein 33; TRIM33; KIAA1113
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TIF1   gamma  
• Gene symbol
  TRIM24
• Short name
  Anti-T1 gamma
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TIF1 gamma Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11812
• Gene
  TRIM24
• Long gene name
  tripartite motif containing 24
• Synonyms gene
  • TIF1
• Synonyms gene name
  • transcriptional intermediary factor 1
  • tripartite motif-containing 24
• Synonyms
  • hTIF1
  • Tif1a
  • RNF82
  • TIF1A
• GenBank acession
  • AF009353
• Locus
  7q33-q34
• Discovery year
  1998-12-18
• Entrez gene record
  8805
• Pubmed identfication
  • 9115274
  • 9191165
• RefSeq identity
  • NM_015905
• Classification
  • Ring finger proteins
  • Bromodomain containing
  • Tripartite motif containing
  • PHD finger proteins
• VEGA ID
  OTTHUMG00000155820

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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