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Synonyms
Prothymosin alpha, PTMA, TMSA
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Alternative_names
Prothymosin alpha, PTMA, TMSA
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Recombinant
No
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Purity by SDS PAGE
> 99%
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Assay
HPLC
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Endotoxin Level
< 1.0 EU per/mg
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Molecular Weight
3.1 kDa
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Lyophilized
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Reconstitution Instructions
Reconstitute in Trifluoro acetic acid
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Background Information
Thymosin α1 is a peptide fragment derived from prothymosin alpha, a protein that in humans is encoded by the PTMA gene. Thymosin α1 is believed to be a major component of Thymosin Fraction 5 responsible for the activity of that preparation in restoring immune function in animals lacking thymus glands. It was the first of the peptides from Thymosin Fraction 5 to be completely sequenced and synthesized. Unlike β thymosins, to which it is genetically and chemically unrelated, thymosin α1 is produced as a 28-amino acid fragment, from a longer, 113-amino acid precursor, prothymosin α. It has been found to enhance cell-mediated immunity in humans as well as experimental animals.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Additional description
The Thymosin alpha 1 is a α- or alpha protein sometimes glycoprotein present in blood.