Thapsigargin
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Catalog numberT339250
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PricePlease ask
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Size1 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityIn Stock
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Cas number67526-95-8
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Chemical s molecular weight650.75
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Chemical s main applicationsA widely used inhibitor of the ubiquitous sarco-endoplasmic reticulum Ca(2+)-ATPases in mammalian cells. It acts as a potent, cell-permeable, IP3-independent intracellular calcium releaser that blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostatin. It induces apoptosis by disrupting intracellular free Ca2+ levels.
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Chemical s categoryApoptosis, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
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Other nameOctanoic Acid (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b- decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl Ester; (-)-Thapsigargin; Octanoic Acid [3S-[3α,3aβ,4α,6β,6aβ,7β,8α(Z),9bα]]-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl Ester;
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Chemical s formulaC34H50O12
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Physical propertiesWhite to Off-White Solid
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Melting temperature84-90°C
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Boiling temperatureNo Data Available
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Chemical s soluble inChloroform (Slightly), Methanol (Slightly, Heated)
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Stability conditionsNo Data Available
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Storage-20˚C Freezer
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Gene target
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Short nameThapsigargin
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Alternative nameThapsigargin
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