TCF7L1 Antibody

• Catalog number
  R32325
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TCF7L1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  Optimal dilution of the TCF7L1 antibody should be determined by the researcher.
• Intented use
  This TCF7L1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9HCS4
• Purity
  Antigen affinity
• Description
  Transcription factor 7-like 1 (T-cell specific, HMG-box), also known as TCF7L1, is a human gene. This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence.
• Immunogen
  Amino acids SFPATLHAHQALPVLQAQPLSLVTKSAH of human TCF7L1 were used as the immunogen for the TCF7L1 antibody.
• Storage
  After reconstitution, the TCF7L1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Nuclear
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TCF7L1  
• Gene symbol
  TCF7L1, TCF7L1-IT1
• Short name
  Anti-TCF7L1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to TCF7L1
• Alternative technique
  antibodies
• Alternative to gene target
  transcription factor 7-like 1 (T-cell specific, HMG-box), TCF7L1 and IDBG-58889 and ENSG00000152284 and 83439, transcription regulatory region DNA binding, nuclei, Tcf7l1 and IDBG-157940 and ENSMUSG00000055799 and 21415

Gene info

• Identity
  HGNC:11640
• Gene
  TCF7L1
• Long gene name
  transcription factor 7 like 1
• Synonyms gene
  • TCF3
• Synonyms gene name
  • transcription factor 7-like 1 (T-cell specific, HMG-box)
• GenBank acession
  • X62870
• Locus
  2p11.2
• Discovery year
  1998-01-20
• Entrez gene record
  83439
• Pubmed identfication
  • 1741298
  • 11085512
• RefSeq identity
  • NM_031283
• Classification
  • TCF/LEF transcription factor family
  • Wnt enhanceosome complex
• VEGA ID
  OTTHUMG00000130026

Gene info

• Identity
  HGNC:41388
• Gene
  TCF7L1-IT1
• Long gene name
  TCF7L1 intronic transcript 1
• Synonyms gene name
  • TCF7L1 intronic transcript 1 (non-protein coding)
• Locus
  2p11.2
• Discovery year
  2011-05-19
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000153211

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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