TAZ Antibody

• Catalog number
  bs-12367R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TAZ Primary Polyclonal Antibody
• Also known as
  TAZ PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TAZ
• Specificity
  This is a highly specific antibody against TAZ.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  15-70/400
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TAZ
• Gene ID number
  25937
• Swiss Prot
  Q9GZV5
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  TAZ; WW domain-containing transcription regulator protein 1; Transcriptional coactivator with PDZ-binding motif; WWTR1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TAZ  
• Gene symbol
  WWTR1, ZBTB18, TAFAZZIN
• Short name
  Anti-TAZ
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TAZ Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:24042
• Gene
  WWTR1
• Long gene name
  WW domain containing transcription regulator 1
• Synonyms
  • TAZ
  • DKFZp586I1419
• Synonyms name
  • transcriptional coactivator with PDZ-binding motif
• GenBank acession
  • AK022036
• Locus
  3q25.1
• Discovery year
  2004-12-03
• Entrez gene record
  25937
• Pubmed identfication
  • 11118213
  • 15096513
• RefSeq identity
  • NM_015472
• VEGA ID
  OTTHUMG00000159614

Gene info

• Identity
  HGNC:13030
• Gene
  ZBTB18
• Long gene name
  zinc finger and BTB domain containing 18
• Synonyms gene
  • ZNF238
• Synonyms gene name
  • zinc finger protein 238
• Synonyms
  • C2H2-171
  • TAZ-1
  • RP58
• GenBank acession
  • U38896
• Locus
  1q44
• Discovery year
  1998-11-19
• Entrez gene record
  10472
• Pubmed identfication
  • 9568537
  • 9013868
• RefSeq identity
  • NM_205768
• Classification
  • BTB domain containing
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000040013

Gene info

• Identity
  HGNC:11577
• Gene
  TAFAZZIN
• Long gene name
  tafazzin, phospholipid-lysophospholipid transacylase
• Synonyms gene
  • CMD3A
  • EFE2
  • EFE
  • TAZ
• Synonyms gene name
  • endocardial fibroelastosis 2
  • cardiomyopathy, dilated 3A (X-linked)
  • tafazzin
• Synonyms
  • BTHS
  • G4.5
  • TAZ1
• Synonyms name
  • Barth syndrome
• GenBank acession
  • X92762
• Locus
  Xq28
• Discovery year
  1989-05-29
• Entrez gene record
  6901
• Pubmed identfication
  • 8042670
• VEGA ID
  OTTHUMG00000033190
• Locus Specific Databases
  • TAZbase: Mutation registry for Barth syndrome
  • LRG_131

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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