Syncytin 1 Antibody

• Catalog number
  bs-2962R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Syncytin 1 Primary Polyclonal Antibody
• Also known as
  Syncytin 1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Syncytin 1
• Specificity
  This is a highly specific antibody against Syncytin 1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  460-510/538
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Syncytin 1
• Gene ID number
  30816
• Swiss Prot
  Q9UQF0
• Tested Applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904). Endogenous envelope proteins may have kept, lost or modified their original function during evolution. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein (SU) mediates receptor recognition, while the transmembrane protein (TM) acts as a class I viral fusion protein. The protein may have at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of membranes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ENV; ENVW; HERVW; ERVWE1; HERV7Q; HERV-7q; HERVWENV; HERV-W-ENV; Syncytin-1; Endogenous retrovirus group W member 1; Env-W; Envelope polyprotein gPr73; Enverin; HERV-7q Envelope protein; HERV-W envelope protein; HERV-W_7q21.2 provirus ancestral Env polyprotein; Syncytin; ERVW-1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Syncytin  
• Gene symbol
  ERVFRD-1, ERVW-1
• Short name
  Anti-Syncytin 1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Syncytin 1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:33823
• Gene
  ERVFRD-1
• Long gene name
  endogenous retrovirus group FRD member 1, envelope
• Synonyms gene name
  • endogenous retrovirus group FRD, member 1
  • endogenous retrovirus group FRD member 1
• Synonyms
  • HERV-W/FRD
  • HERV-FRD
  • envFRD
  • ERVFRDE1
  • syncytin-2
• Synonyms name
  • syncytin 2
• GenBank acession
  • AK075092
  • AK123938
  • AY358244
• Locus
  6p24.2
• Discovery year
  2011-05-05
• Entrez gene record
  405754
• Pubmed identfication
  • 12970426
  • 14557543
  • 15476554
  • 21542922
• RefSeq identity
  • NM_207582
• VEGA ID
  OTTHUMG00000159193

Gene info

• Identity
  HGNC:13525
• Gene
  ERVW-1
• Long gene name
  endogenous retrovirus group W member 1, envelope
• Synonyms gene
  • ERVWE1
• Synonyms gene name
  • endogenous retroviral family W, env(C7), member 1
  • endogenous retrovirus group W, member 1
  • endogenous retrovirus group W member 1
• Synonyms
  • HERV-W
  • HERV-W-ENV
  • HERVW
  • HERV-7q
  • envW
• Synonyms name
  • envelope protein
  • HERV-W Env glycoprotein
  • enverin
  • syncytin-1
  • HERV-tryptophan envelope protein
  • HERV-W{7q21.1} provirus ancestral Env polyprotein
  • HERV-7q envelope protein
  • envelope glycoprotein
  • syncytin
• GenBank acession
  • AF208161
• Locus
  7q21.2
• Discovery year
  2000-09-20
• Entrez gene record
  30816
• Pubmed identfication
  • 9835022
  • 9882319
  • 21542922
• RefSeq identity
  • NM_014590
• VEGA ID
  OTTHUMG00000131249

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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