Synaptojanin 1 Antibody

• Catalog number
  bs-11376R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Synaptojanin 1 Antibody
• Also known as
  Synaptojanin 1 Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Synaptojanin 1
• Specificity
  This is a highly specific antibody against Synaptojanin 1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Synaptojanin/INPP5G
• Gene ID number
  8867
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Synaptojanins are characterized by an N-terminal SAC1-like sequence, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4,5-bisphosphate as a substrate. Synaptojanins exist as two isoforms, synaptojanin 1 and 2, which differ in the C-terminal domain, and each isoform has multiple variants produced by alternative splicing. Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues. Eight splice variants of synaptojanin 2 have been detected, including a brain specific isoform. Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  5-trisphosphate 5-phosphatase 1; Inositol 5' phosphatase; INPP 5G; INPP5G; KIAA0910; Polyphosphoinositide phosphatase; Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 1; Synaptic inositol 145 trisphosphate 5 phosphatase 1; Synaptic inositol-1 antibody Synaptic inositol-145-trisphosphate 5-phosphatase 1; Synaptojanin 1; Synaptojanin 1 polyphosphoinositide phosphatase; Synaptojanin-1; Synaptojanin1; Synj 1; Synj1; SYNJ1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Synaptojanin  
• Gene symbol
  SYNJ1
• Short name
  Anti-Synaptojanin 1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Synaptojanin 1 Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11503
• Gene
  SYNJ1
• Long gene name
  synaptojanin 1
• Synonyms
  • INPP5G
  • PARK20
• Synonyms name
  • phosphoinositide 5-phosphatase
  • synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1
  • inositol polyphosphate-5-phosphatase G
• GenBank acession
  • AF009040
• Locus
  21q22.11
• Discovery year
  1999-10-14
• Entrez gene record
  8867
• Pubmed identfication
  • 9428629
  • 10773674
  • 24609975
  • 14704270
• RefSeq identity
  • NM_003895
• Classification
  • Phosphoinositide phosphatases
• VEGA ID
  OTTHUMG00000064926

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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