Sulfo-NHS-LC-Biotin

• Catalog number
  2326-100
• Price
  Please ask
• Size
  100 mg

• Alternative_name
  Sulfosuccinimidyl 6-(biotinamido) Hexanoate; Biotinamidohexanoic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt
• Description
  KEY FEATURES: • Amine-reactive; has a spacer with arm length of 22.4 Å which helps to minimize steric hindrance to biotin labeling • More water-soluble than the corresponding NHS compound without the sulfo group • Membrane-impermeable • Forms permanent amide bonds and the spacer arm cannot be cleaved APPLICATIONS: • Sulfo-NHS-LC-Biotin is ideal for biotinylating antibody or protein that can then be used for protein detection, purification or immobilization • Sulfo-NHS-LC-Biotin is particularly useful for targeting cell surface proteins due to the membrane-impermeability of this reagent
• CAS Number
  127062-22-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₄H₁₈O₈N₃S₂Na
• Molecular Weight
  556.59
• Cell Permeable
  No
• Purity
  ≥90% by NMR
• Solubilities
  H₂O (~ 20 mg/ml)
• Handling
  Protect from moisture
• Tag Line
  Sulfo-NHS-LC-Biotin is a water-soluble protein biotinylation reagent.
• Storage Condition
  -20 ̊C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00078534
• PubChem CID
  16219001
• PubChem CID Link
• SMILES
  O=C([MH]1)NC2C1CSC2CCCCC(NCCCCCC(ON3C(C(S(=O)(O[Na])=O)CC3=O)=O)=O)=O
• InChi
  InChI=1S/C20H30N4O9S2.Na/c25-15(7-4-3-6-13-18-12(11-34-13)22-20(29)23-18)21-9-5-1-2-8-17(27)33-24-16(26)10-14(19(24)28)35(30,31)32;/h12-14,18H,1-11H2,(H,21,25)(H2,22,23,29)(H,30,31,32);
• InChi Key
  RDSJVNGBJUJRRW-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes
• Properties
  Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Conjugation
  Biotinylated

• Gene target
  Sulfo-NHS-LC  
• Gene symbol
  NHS, NHS-AS1, PTPN7, CT83
• Short name
  Sulfo-NHS-LC-
• Label
  NHS-LC-Biotin
• Alternative name
  Sulfo-NHS-LC-biotinilated

Gene info

• Identity
  HGNC:7820
• Gene
  NHS
• Long gene name
  NHS actin remodeling regulator
• Synonyms gene name
  • Nance-Horan syndrome (congenital cataracts and dental anomalies)
• Locus
  Xp22.2-p22.13
• Discovery year
  1989-06-30
• Entrez gene record
  4810
• Pubmed identfication
  • 20332100
• RefSeq identity
  • NM_198270
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000022799
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:40403
• Gene
  NHS-AS1
• Long gene name
  NHS antisense RNA 1
• Synonyms gene name
  • NHS antisense RNA 1 (non-protein coding)
• Locus
  Xp22.13
• Discovery year
  2011-07-29
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000021203

Gene info

• Identity
  HGNC:9659
• Gene
  PTPN7
• Long gene name
  protein tyrosine phosphatase non-receptor type 7
• Synonyms
  • HEPTP
  • LC-PTP
• GenBank acession
  • BC001746
• Locus
  1q32.1
• Discovery year
  1993-03-03
• Entrez gene record
  5778
• Pubmed identfication
  • 1510684
• RefSeq identity
  • NM_002832
• Classification
  • Protein tyrosine phosphatases non-receptor type
• VEGA ID
  OTTHUMG00000035931

Gene info

• Identity
  HGNC:33494
• Gene
  CT83
• Long gene name
  cancer/testis antigen 83
• Synonyms gene
  • CXorf61
• Synonyms gene name
  • chromosome X open reading frame 61
• Synonyms
  • KK-LC-1
  • FLJ20611
  • FLJ22913
• Synonyms name
  • Kita-kyushu lung cancer antigen 1
• GenBank acession
  • BC062223
• Locus
  Xq23
• Discovery year
  2007-06-20
• Entrez gene record
  203413
• Pubmed identfication
  • 16651449
• RefSeq identity
  • NM_001017978
• VEGA ID
  OTTHUMG00000022244

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