Suc-Leu-Leu-Val-Tyr-AMC

  • Catalog number
    1833-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    Suc-LLVY-AMC; Proteasome Substrate; Calpain Substrate
  • Description
    A widely used fluorogenic substrate for 20S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored fluorometrically. λex: 340 - 360 nm; λem: 440 - 460 nm.
  • CAS Number
    94367-21-2
  • Structure Available
    Yes
  • Peptide sequence
    Suc-Leu-Leu-Val-Tyr-AMC
  • Salt Form
    No
  • Molecular Formula
    C₄₀H₅₃N₅O₁₀
  • Molecular Weight
    763.88
  • Cell Permeable
    No
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~ 5 mM)
  • Handling
    Protect from moisture and light
  • Tag Line
    A proteasome substrate
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD00080248
  • PubChem CID
    10234210
  • SMILES
    CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)CCC(=O)O
  • InChi
    InChI=1S/C40H53N5O10/c1-21(2)16-29(42-33(47)14-15-34(48)49)38(52)43-30(17-22(3)4)39(53)45-36(23(5)6)40(54)44-31(19-25-8-11-27(46)12-9-25)37 (51)41-26-10-13-28-24(7)18-35(50)55-32(28)20-26/h8-13,18,20-23,29-31,36,46H,14-17,19H2,1-7H3,(H,41,51)(H,42,47)(H,43,52)(H,44,54)(H,45,53)(H,48, 49)/t29-,30-,31-,36-/m0/s1
  • InChi Key
    UVFAEQZFLBGVRM-MSMWPWNWSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Suc-Leu-Leu-Val-Tyr-AMC
  • Alternative name
    Suc-L-leucine-L-leucine-L-valine-L-tyrosine-AMC
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