Suc-Leu-Leu-Val-Tyr-AMC
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Catalog number1833-25
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PricePlease ask
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Size25 mg
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Alternative_nameSuc-LLVY-AMC; Proteasome Substrate; Calpain Substrate
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DescriptionA widely used fluorogenic substrate for 20S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored fluorometrically. λex: 340 - 360 nm; λem: 440 - 460 nm.
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CAS Number94367-21-2
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Structure AvailableYes
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Peptide sequenceSuc-Leu-Leu-Val-Tyr-AMC
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Salt FormNo
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Molecular FormulaC₄₀H₅₃N₅O₁₀
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Molecular Weight763.88
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Cell PermeableNo
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Purity≥98% by HPLC
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SolubilitiesDMSO (~ 5 mM)
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HandlingProtect from moisture and light
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Tag LineA proteasome substrate
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD00080248
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PubChem CID10234210
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SMILESCC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)CCC(=O)O
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InChiInChI=1S/C40H53N5O10/c1-21(2)16-29(42-33(47)14-15-34(48)49)38(52)43-30(17-22(3)4)39(53)45-36(23(5)6)40(54)44-31(19-25-8-11-27(46)12-9-25)37 (51)41-26-10-13-28-24(7)18-35(50)55-32(28)20-26/h8-13,18,20-23,29-31,36,46H,14-17,19H2,1-7H3,(H,41,51)(H,42,47)(H,43,52)(H,44,54)(H,45,53)(H,48, 49)/t29-,30-,31-,36-/m0/s1
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InChi KeyUVFAEQZFLBGVRM-MSMWPWNWSA-N
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MSDS AvailableYes
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Gene target
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Short nameSuc-Leu-Leu-Val-Tyr-AMC
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Alternative nameSuc-L-leucine-L-leucine-L-valine-L-tyrosine-AMC
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