MEF2B Antibody

• Catalog number
  bs-9470R
• Price
  Please ask
• Size
  0.1ml

• Long name
  MEF2B Primary Polyclonal Antibody
• Also known as
  MEF2B PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  MEF2B
• Specificity
  This is a highly specific antibody against MEF2B.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MEF2B
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PRDM3; MADS box transcription enhancer factor 2; MDS1 EVI1; Mef2b; MEF2B_HUMAN; MEF-2B; myocyte enhancer factor 2B; myocyte specic enhancer factor 2B; Myocyte-specic enhancer factor 2B; RSRFR2; serum response factor like protein 2; Serum response factor-like protein 2; XMEF2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MEF2B  
• Gene symbol
  BORCS8-MEF2B, MEF2B
• Short name
  Anti-MEF2B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  MEF2B Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:39979
• Gene
  BORCS8-MEF2B
• Long gene name
  BORCS8-MEF2B readthrough
• Synonyms gene
  • MEF2BNB-MEF2B
• Synonyms gene name
  • MEF2BNB-MEF2B readthrough
• Locus
  19p13.11
• Discovery year
  2011-04-19
• Entrez gene record
  4207
• RefSeq identity
  • NM_005919.3
• VEGA ID
  OTTHUMG00000154572

Gene info

• Identity
  HGNC:6995
• Gene
  MEF2B
• Long gene name
  myocyte enhancer factor 2B
• Synonyms
  • RSRFR2
• GenBank acession
  • X63380
• Locus
  19p13.11
• Discovery year
  1995-02-08
• Entrez gene record
  100271849
• Pubmed identfication
  • 1516833
  • 8575763
• RefSeq identity
  • NM_005919
• Classification
  • MADS box family
  • Myocyte enhancer factor 2 proteins
• VEGA ID
  OTTHUMG00000161595

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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