SQSTM1 (1336CT763.152.125) Monoclonal Antibody
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Catalog number
bsm-51287M
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Price
Please ask
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Size
0.1ml
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Long name
SQSTM1 (1336CT763.152.125) Monoclonal Antibody
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Also known as
SQSTM1 (1336CT763.152.125) Monoclonal Antibody
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
SQSTM1
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Specificity
This is a highly specific antibody against SQSTM1.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Monoclonal
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Clone number
1336CT763.152.125
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Source
This SQSTM1 antibody is generated from mice immunized with a recombinant protein.
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Gene ID number
8878
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Swiss Prot
Q13501
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Tested Applications
WB
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Recommended dilutions
WB(1:1000)
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Cross reactivity
Human
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
p60; p62; A170; OSIL; PDB3; ZIP3; p62B; FTDALS3; Sequestosome-1; EBI3-associated protein of 60 kDa; EBIAP; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin-binding protein p62; SQSTM1; ORCA
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translation
anticorps
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Gene target
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Gene symbol
SQSTM1
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Short name
Anti-SQSTM1
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Technique
Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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Host
Mouse (Mus musculus)
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Isotype
Immunoglobulin G (IgG)1 κ
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Alternative name
SQSTM1 (1336CT763.152.125) Monoclonal Antibody
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Alternative technique
antibodies
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Alternative to gene target
sequestosome 1, A170 and OSIL and p60 and p62 and p62B and PDB3 and ZIP3, SQSTM1 and IDBG-61811 and ENSG00000161011 and 8878, K63-linked polyubiquitin binding, nuclei, Sqstm1 and IDBG-168358 and ENSMUSG00000015837 and 18412, BT.105440 and IDBG-640935 and ENSBTAG00000015591 and 338045
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Gene info
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Identity
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Gene
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Long gene name
sequestosome 1
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Synonyms gene
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Synonyms gene name
- Paget disease of bone 3
- oxidative stress induced like
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2000-06-13
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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