SPINK1 (Pancreatic Secretory Trypsin Inhibitor, Serine Protease Inhibitor Kazal-type 1, Tumor-associated Trypsin Inhibitor, TATI, PSTI)

• Catalog number
  GEN644689
• Price
  Please ask
• Size
  100ug

• Also known as
  SPINK1
• Other names
  N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a,k
• Clone
  4D4
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human SPINK1.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein A affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.

• Gene target
  SPINK1   Pancreatic   Secretory   Trypsin   Inhibitor   Serine   Protease   Inhibitor   Kazal   Tumor-associated   Trypsin   Inhibitor   TATI   PSTI  
• Gene symbol
  SPINK1
• Short name
  SPINK1 (Pancreatic Secretory Trypsin Inhibitor, Serine Protease Inhibitor Kazal- 1, Tumor-associated Trypsin Inhibitor, TATI, PSTI)
• Alternative name
  Anti-SPINK1 (Pancreatic Secretory Trypsin Inhibitor, Serine Protease Inhibitor Kazal-type 1, Tumor-associated Trypsin Inhibitor, TATI, PSTI)
• Tissue
  tumor

Gene info

• Identity
  HGNC:11244
• Gene
  SPINK1
• Long gene name
  serine peptidase inhibitor Kazal type 1
• Synonyms gene name
  • serine protease inhibitor, Kazal type 1
• Synonyms
  • Spink3
  • PCTT
  • PSTI
  • TATI
• Locus
  5q32
• Discovery year
  1988-06-27
• Entrez gene record
  6690
• RefSeq identity
  • NM_003122
• Classification
  • Serine peptidase inhibitors, Kazal type
• VEGA ID
  OTTHUMG00000129730

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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