PTH 1-84/Parathyroid hormone/Parathormone

• Catalog number
  E21-010
• Price
  Please ask
• Size
  10ug

• Shipping_Temperature
  Ambient
• Product_State
  Lyophilized
• Formulation_Description
  Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 5% Mannitol, pH 4.0.
• Storage
  Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Reconstitution
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Background
  Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids.
• Alternative Names
  Parathyroid Hormone; PTH; Parathormone; Parathyrin
• Expression system
  E.coli
• Description
  Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.

• Gene target
  PTH   1-84/Parathyroid   hormone/Parathormone  
• Gene symbol
  PTH, SPAG8, GOLGA5, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, ERGIC3, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1
• Short name
  PTH 1-84/Parathyroid hormone/Parathormone
• Species
  Human
• Alternative name
  parathyroid hormone 1-84/Parathyroid hormone/Parathormone
• Alternative to gene target
  parathyroid hormone, PTH1, PTH and IDBG-32891 and ENSG00000152266 and 5741, peptide hormone receptor binding, Extracellular, Pth and IDBG-207092 and ENSMUSG00000059077 and 19226, PTH and IDBG-632953 and ENSBTAG00000019080 and 280903

Gene info

• Identity
  HGNC:9606
• Gene
  PTH
• Long gene name
  parathyroid hormone
• Synonyms
  • PTH1
• Synonyms name
  • parathyrin
  • parathormone
  • parathyroid hormone 1
  • preproparathyroid hormone
  • prepro-PTH
• GenBank acession
  • J00301
• Locus
  11p15.3
• Discovery year
  2001-06-22
• Entrez gene record
  5741
• Pubmed identfication
  • 1672845
• RefSeq identity
  • NM_000315
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000165785

Gene info

• Identity
  HGNC:14105
• Gene
  SPAG8
• Long gene name
  sperm associated antigen 8
• Synonyms
  • hSMP-1
  • HSD-1
  • BS-84
  • SPAG3
  • CT142
• GenBank acession
  • U12978
• Locus
  9p13.3
• Discovery year
  2001-01-10
• Entrez gene record
  26206
• Pubmed identfication
  • 10500252
  • 8788182
• RefSeq identity
  • NM_012436
• VEGA ID
  OTTHUMG00000019875

Gene info

• Identity
  HGNC:4428
• Gene
  GOLGA5
• Long gene name
  golgin A5
• Synonyms gene name
  • golgi autoantigen, golgin subfamily a, 5
• Synonyms
  • ret-II
  • golgin-84
  • rfg5
  • GOLIM5
• Synonyms name
  • golgi integral membrane protein 5
• GenBank acession
  • AF085199
• Locus
  14q32.12
• Discovery year
  1999-04-28
• Entrez gene record
  9950
• Pubmed identfication
  • 2734021
  • 9443391
  • 15004235
• Classification
  • Golgins
• VEGA ID
  OTTHUMG00000171217

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:15927
• Gene
  ERGIC3
• Long gene name
  ERGIC and golgi 3
• Synonyms gene
  • SDBCAG84
  • C20orf47
• Synonyms gene name
  • serologically defined breast cancer antigen 84
  • chromosome 20 open reading frame 47
• Synonyms
  • CGI-54
  • PRO0989
  • NY-BR-84
  • Erv46
• GenBank acession
  • AF077030
• Locus
  20q11.22
• Discovery year
  2001-07-31
• Entrez gene record
  51614
• Pubmed identfication
  • 10810093
• RefSeq identity
  • NM_015966
• VEGA ID
  OTTHUMG00000032346

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

Gene info

• Identity
  HGNC:31488
• Gene
  MIR101-1
• Long gene name
  microRNA 101-1
• Synonyms gene
  • MIRN101-1
• Synonyms
  • hsa-mir-101-1
• Locus
  1p31.3
• Discovery year
  2004-04-23
• Entrez gene record
  406893
• RefSeq identity
  • NR_029516
• Classification
  • MicroRNA MIR101 family

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