SNX6 (335CT6.4.6) Monoclonal Antibody

• Catalog number
  bsm-51105M
• Price
  Please ask
• Size
  0.1ml

• Long name
  SNX6 (335CT6.4.6) Monoclonal Antibody
• Also known as
  SNX6 (335CT6.4.6) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SNX6
• Specificity
  This is a highly specific antibody against SNX6.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  335CT6.4.6
• Source
  This SNX6 monoclonal antibody is generated from mouse immunized with SNX6 recombinant protein.
• Gene ID number
  58533
• Swiss Prot
  Q9UNH7
• Tested Applications
  WB
• Recommended dilutions
  WB(1:1000~16000)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Involved in several stages of intracellular trafficking. Interacts with membranes phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bisphosphate (Probable). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex (PubMed:19935774). The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Does not have in vitro vesicle-to-membrane remodeling activity (PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptor IGF2R (PubMed:17148574). May function as link between transport vesicles and dynactin (Probable). Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network (PubMed:20354142). Involved in E-cadherin sorting and degradation; inhibits PIP5K1C isoform 3-mediated E-cadherin degradation (PubMed:24610942). In association with GIT1 involved in EGFR degradation. Promotes lysosomal degradation of CDKN1B (By similarity). May contribute to transcription regulation (Probable).
• Purification method
  Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  TFAF2; MSTP010; Sorting nexin-6; TRAF4-associated factor 2; SNX6
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  SNX6   335CT6   Monoclonal  
• Gene symbol
  SNX6
• Short name
  Anti-SNX6
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)1
• Alternative name
  SNX6 (335CT6.4.6) Monoclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  sorting nexin 6, SNX6 and IDBG-4564 and ENSG00000129515 and 58533, protein homodimerization activity, nuclei, Snx6 and IDBG-139633 and ENSMUSG00000005656 and 72183, SNX6 and IDBG-632423 and ENSBTAG00000012873 and 532685

Gene info

• Identity
  HGNC:14970
• Gene
  SNX6
• Long gene name
  sorting nexin 6
• GenBank acession
  • AF121856
• Locus
  14q13.1
• Discovery year
  2001-04-10
• Entrez gene record
  58533
• Pubmed identfication
  • 11279102
• Classification
  • PX-BAR domain containing
  • Sorting nexins
• VEGA ID
  OTTHUMG00000140213

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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