SMER3,E3 UB ligase inhibitor
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Catalog number
SIH-341-50MG
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Price
Please ask
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Size
50 mg
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Research Area s
Cancer , Apoptosis
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Category
Small Molecules
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Product Type
Inhibitor
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CAS No
67200-34-4
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MolecularFormula
C11H4N4O2
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Molecular Weight
224.18
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Purity
>98%
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Solubility
Soluble in 75 mM DMSO
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Appearance
Yellow Solid
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Storage Temperature
-20°C
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Shipping Temperature
Shipped Ambient
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Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
MeSH Data
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Name
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Concept
Scope note:
A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
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Tree numbers
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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